ArticleSaudi medical journal2019
Platelet/lymphocyte ratio is an independent predictor for osteoporosis.
Article in Saudi medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Association between immune-inflammatory index and osteoporosis: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- Association of neutrophil to lymphocyte ratio with bone mineral density in post-menopausal women: a systematic review and meta-analysis.BMC women's health · 2024Pooled it
- Platelet Features and Derivatives in Osteoporosis: A Rational and Systematic Review on the Best Evidence.International journal of molecular sciences · 2020Pooled it
- Construction and internal validation of a risk prediction model for rapid bone loss during aromatase inhibitor therapy.Frontiers in oncology · 2026Article
- Exploring the Association Between Platelet Count, the Systemic Immune Inflammation Index, and Fracture Risk in Postmenopausal Women with Osteoporosis: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- The unexplored relationship between spontaneous osteoclastogenesis and platelets in osteoporosis.Frontiers in medicine · 2025Article
- Identification of key genes and long non‑coding RNA expression profiles in osteoporosis with rheumatoid arthritis based on bioinformatics analysis.BMC musculoskeletal disorders · 2024Article
- Association of lymphocyte subsets and cytokines with bone metabolism: a retrospective, cross-sectional study.BMC musculoskeletal disorders · 2024Article
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- The Potential Therapeutic Effects of Platelet-Derived Biomaterials on Osteoporosis: A Comprehensive Review of Current Evidence.International journal of biomaterials · 2023Review
- Associations of the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio with Osteoporosis: A Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Article
- Inflammatory Markers as a Predictor of Postmenopausal Osteoporosis: Cross-sectional study from Sultan Qaboos University Hospital.Sultan Qaboos University medical journal · 2022Article
- Associations of Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio and Monocyte-to-Lymphocyte Ratio with Osteoporosis and Incident Vertebral Fracture in Postmenopausal Women with Rheumatoid Arthritis: A Single-Center Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2022Article
- Effect of Lymphocyte Subsets on Bone Density in Senile Osteoporosis: A Retrospective Study.Journal of immunology research · 2022Article
- Vitamin D and Platelets: A Menacing Duo in COVID-19 and Potential Relation to Bone Remodeling.International journal of molecular sciences · 2021Review
- Blood factors as biomarkers in osteoporosis: points from the COVID-19 era.Trends in endocrinology and metabolism: TEM · 2021Review
- Association of Hydrogen Sulfide with Femoral Bone Mineral Density in Osteoporosis Patients: A Preliminary Study.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- A correlative studies between osteoporosis and blood cell composition: Implications for auxiliary diagnosis of osteoporosis.Medicine · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the intercourse between the platelet/lymphocyte (P/L) and neutrophil/lymphocyte ratio (N/L), and vitamin D (Vit-D) levels in low bone mineral density (BMD) of women. Methods: Two hundred fifty-two postmenopausal female outpatients who were admitted to the obstetrics and gynecology and physical therapy clinics between July 2016 and December 2017 were retrospectively analyzed. The patients were grouped in relation to their T-score (normal [n=92], osteopenia [n=112], and PMO [n=48]). The serum levels of P/L, N/L, Vit-D, BMD and complete blood count of the patients were retrospectively examined. Results: The median P/L was significantly higher and Vit-D levels were significantly lower in the PMO group (130.75 [52.89-385] versus 123.05 [54-232.5], p=0.02 and 15.4 [4-34] versus 20.1 [4-47], p=0.003). While BMD and P/L were negatively correlated, a positive correlation between BMD and Vit-D was found. Vitamin D levels were negatively correlated with P/L (p less than 0.001) and N/L (p=0.04). Older age (≥65 years), Vit-D deficiency and P/L values greater than 125.06 were found as independent prognostic factors for PMO in regression analysis. Conclusion: Higher P/L seems to be a quite simple marker to help predict postmenopausal PMO. As seen in our study, having low levels of Vit-D is crucial for PMO.
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Registered trials
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