Evidence map›Paper›PMID 30957053›Full record

ArticleMethods and protocols2019

Protocol for Construction of Rat Nerve Stimulation Cuff Electrodes.

Manolo U Rios, Jesse E Bucksot, Kimiya C Rahebi, Crystal T Engineer, Michael P Kilgard, Seth A Hays

Open access · goldAbstract read
In one paragraph

Article in Methods and protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Manolo U RiosSchool of Brain and Behavioral Sciences, The University of Texas at Dallas, Richardson, TX 75080-3021, USA; manolo.rios@utsouthwestern.edu (M.U.R.); kilgard@utdallas.edu (M.P.K.), seth.hays@utdallas.edu (S.A.H.).
Jesse E BucksotSchool of Biomedical Engineering, The University of Texas at Dallas, Richardson, TX 75080-3021, USA; jesse.bucksot@utdallas.edu.
Kimiya C RahebiTexas Biomedical Device Center (TxBDC), The University of Texas at Dallas, Richardson, TX 75080-3021, USA; kimiyarahebi@gmail.com.
Crystal T EngineerSchool of Brain and Behavioral Sciences, The University of Texas at Dallas, Richardson, TX 75080-3021, USA; manolo.rios@utsouthwestern.edu (M.U.R.); kilgard@utdallas.edu (M.P.K.), seth.hays@utdallas.edu (S.A.H.).
Michael P KilgardSchool of Brain and Behavioral Sciences, The University of Texas at Dallas, Richardson, TX 75080-3021, USA; manolo.rios@utsouthwestern.edu (M.U.R.); kilgard@utdallas.edu (M.P.K.), seth.hays@utdallas.edu (S.A.H.).
Seth A HaysSchool of Brain and Behavioral Sciences, The University of Texas at Dallas, Richardson, TX 75080-3021, USA; manolo.rios@utsouthwestern.edu (M.U.R.); kilgard@utdallas.edu (M.P.K.), seth.hays@utdallas.edu (S.A.H.).
Texas Biomedical Research Institute · USThe University of Texas at Dallas · US

Funding

Enhancing Speech Processing In A Rat Model Of Autism Using Vagus Nerve StimulationR01DC017480 · NIDCD · UNIVERSITY OF TEXAS DALLAS · PI ENGINEER, CRYSTAL T · 2019 to 2023
$2.0M
Vagus Nerve Stimulation Paired with Rehabilitative Training to Enhance PlasticityR01NS085167 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI KILGARD, MICHAEL P, RENNAKER, ROBERT L · 2014 to 2018
$1.9M
Evaluation of the Neuromodulatory Mechanisms of Vagus Nerve Stimulation to Improve Motor Rehabilitation after StrokeR01NS094384 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI HAYS, SETH ALANSON · 2016 to 2020
$1.7M
Enhancing Recovery after Chronic Bilateral Cervical Spinal Cord Injury with Targeted Plasticity TherapyR01NS103803 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI KILGARD, MICHAEL P, RENNAKER, ROBERT L · 2018 to 2022
$1.7M
NIDCD NIH HHS R01 DC017480NINDS NIH HHS R01 NS085167NINDS NIH HHS R01 NS094384NINDS NIH HHS R01 NS103803
6 · The paper itself

Abstract

Peripheral nerve stimulation has emerged as a platform therapy to treat a wide range of disorders. Continued development and translation of these strategies requires that researchers have access to reliable, customizable electrodes for nerve stimulation. Here, we detail procedures to build three different configurations of cuff electrodes with varying numbers and orientations of contacts for nerve stimulation in rats. These designs are built with simple, widely available materials, using platinum-iridium electrodes assembled into polyurethane tubing. Moreover, the designs can easily be customized to increase versatility and individualize for specific stimulation applications. This protocol provides a resource to facilitate the construction and customization of stimulation cuffs to support preclinical nerve stimulation research.

Indexed as

cuff electrodemicro-constructionvagal nervevagus nervevagus nerve stimulation

Identifiers

PMID30957053
PMCPMC6448795
OpenAlexW2917222893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.