Evidence map›Paper›PMID 30956927›Full record

ArticleIEEE access : practical innovations, open solutions2019

Enhancement of Perivascular Spaces Using Densely Connected Deep Convolutional Neural Network.

Euijin Jung, Philip Chikontwe, Xiaopeng Zong, Weili Lin, Dinggang Shen, Sang Hyun Park

Abstract read
In one paragraph

Article in IEEE access : practical innovations, open solutions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Perivascular Space Imaging at Ultrahigh Field MR Imaging.Magnetic resonance imaging clinics of North America · 2021
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Euijin JungDepartment of Robotics Engineering, DGIST, Daegu 42988, South Korea.
Philip ChikontweDepartment of Robotics Engineering, DGIST, Daegu 42988, South Korea.ORCID 0000-0002-6995-2312
Xiaopeng ZongBiomedical Research Imaging Center, Department of Radiology, The University of North Carolina, Chapel Hill, NC 27599, USA.
Weili LinBiomedical Research Imaging Center, Department of Radiology, The University of North Carolina, Chapel Hill, NC 27599, USA.
Dinggang ShenBiomedical Research Imaging Center, Department of Radiology, The University of North Carolina, Chapel Hill, NC 27599, USA.
Sang Hyun ParkDepartment of Robotics Engineering, DGIST, Daegu 42988, South Korea.ORCID 0000-0001-7476-1046

Funding

Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
NIBIB NIH HHS R01 EB006733
6 · The paper itself

Abstract

Perivascular spaces (PVS) in the human brain are related to various brain diseases. However, it is difficult to quantify them due to their thin and blurry appearance. In this paper, we introduce a deep-learning-based method, which can enhance a magnetic resonance (MR) image to better visualize the PVS. To accurately predict the enhanced image, we propose a very deep 3D convolutional neural network that contains densely connected networks with skip connections. The proposed networks can utilize rich contextual information derived from low-level to high-level features and effectively alleviate the gradient vanishing problem caused by the deep layers. The proposed method is evaluated on 17 7T MR images by a twofold cross-validation. The experiments show that our proposed network is much more effective to enhance the PVS than the previous PVS enhancement methods.

Indexed as

deep convolutional neural networkdensely connected networkMRI enhancementPerivascular spacesskip connections

Identifiers

PMID30956927
PMCPMC6448784

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.