Evidence map›Paper›PMID 30956828›Full record

ArticleCase reports in nephrology2019

Rapidly Progressive Glomerulonephritis Secondary to IgA Nephropathy in a Patient with Systemic Lupus Erythematosus.

Amol M Patel, Lily Anne Romero Karam, Stephanie C Fuentes Rojas, Warren E Redfearn, Luan D Truong, Juan M Gonzalez

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Lupus and IgA nephropathy: coexistence or coincident?Wiener klinische Wochenschrift · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Case reports in medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Amol M PatelDepartment of Internal Medicine, Houston Methodist Hospital, Houston, TX, USA.ORCID 0000-0002-0985-8092
Lily Anne Romero KaramDepartment of Internal Medicine, Houston Methodist Hospital, Houston, TX, USA.
Stephanie C Fuentes RojasDepartment of Internal Medicine, Houston Methodist Hospital, Houston, TX, USA.
Warren E RedfearnDepartment of Internal Medicine, Houston Methodist Hospital, Houston, TX, USA.
Luan D TruongDepartment of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Juan M GonzalezDepartment of Internal Medicine, Division of Nephrology, Houston, TX, USA.
Methodist Hospital · USMethodist Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lupus nephritis is a common manifestation of systemic lupus erythematosus (SLE). IgA nephropathy is a common type of primary glomerulonephritis. Renal manifestations in SLE patients are often due to lupus nephritis; however, renal diseases unrelated to lupus nephritis are rarely reported. While crescentic IgA nephropathy with rapid clinical progression is rare, its development in patients with SLE in the absence of lupus nephritis is even more unusual. A 74-year-old woman with a history of SLE without known renal involvement, chronic kidney disease stage IIIa, congestive heart failure, hypertension, and type 2 diabetes mellitus presented with acute kidney injury. Her creatinine continued to rise rapidly. Renal biopsy revealed mesangial proliferative glomerulonephritis with crescent formation. Immunofluorescent staining showed IgA and C3 mesangial deposition and absence of C4 and C1q, consistent with IgA nephropathy. She received a course of methylprednisolone and plasmapheresis. Unfortunately, her renal function continued to deteriorate, and she was started on hemodialysis which was continued after hospital discharge. This case illustrates crescentic IgA nephropathy without lupus nephritis as the cause of acute kidney injury in a patient with SLE. It highlights the observation that renal diseases other than lupus nephritis can develop in SLE patients.

Identifiers

PMID30956828
PMCPMC6425374
OpenAlexW2920375335

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.