Evidence map›Paper›PMID 30956730›Full record

ArticleDisease markers2019

High Expression of LTBP2 Contributes to Poor Prognosis in Colorectal Cancer Patients and Correlates with the Mesenchymal Colorectal Cancer Subtype.

Ying Huang, Guihua Wang, Chunmei Zhao, Rong Geng, Shu Zhang, Wei Wang, Jing Chen, Huimin Liu, Xudong Wang

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2).Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ying HuangDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Guihua WangDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Chunmei ZhaoDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Rong GengDepartment of Cell Biology, School of Basic Medicine, Nanjing Medical University, Nanjing, 211166 JS, China.
Shu ZhangDepartment of Pathology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Wei WangDepartment of Pathology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Jing ChenDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Huimin LiuDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.
Xudong WangDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001 JS, China.ORCID 0000-0002-3522-3971
Nantong University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a complex and heterogeneous disease with four consensus molecular subtypes (CMS1-4). LTBP2 is a member of the fibrillin/LTBP super family and plays a critical role in tumorigenesis by activating TGF-

Indexed as

Biomarkers, TumorCaco-2 CellsColorectal NeoplasmsEpithelial-Mesenchymal TransitionFemaleHT29 CellsHumansLatent TGF-beta Binding ProteinsMaleMiddle AgedRNA, MessengerUp-RegulationBiomarkers, TumorLatent TGF-beta Binding ProteinsLTBP2 protein, humanRNA, Messenger

Identifiers

PMID30956730
PMCPMC6431450
OpenAlexW2921895902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.