ArticleApplied physics. B, Lasers and optics2018
Laser spectroscopy for breath analysis: towards clinical implementation.
Article in Applied physics. B, Lasers and optics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04556435 (Analysis of Volatile Chemicals in the Breath of Lung Cancer Patients Using Infrared Spectroscopy), which is not on this map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of Volatile Chemicals in the Breath of Lung Cancer Patients Using Infrared Spectroscopy
Who cites it
39 citing papers in PubMed, 206 citations in OpenAlex.
- High inhaled oxygen concentration quadruples exhaled CO in healthy volunteers monitored by a highly sensitive laser spectrometer.Scientific reports · 2019Trial
- Intelligent Algorithm-Assisted Indirect Absorption Spectroscopy for Trace Gas Sensing.Sensors (Basel, Switzerland) · 2026Review
- Real-Time Breath Diagnostics: Linking Molecular Pathways, Measurement Technologies, and Clinical Translation.International journal of molecular sciences · 2026Review
- Detecting Bacteria in Their Mammalian Hosts Using Metabolism-Targeted [ACS central science · 2026Article
- [Advances in the application of exhaled breath analysis technology in the detection and diagnosis of liver failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Review
- COACS omega · 2025Article
- The exhaled breath pattern as a potential method for biometrics identification.Scientific reports · 2025Article
- The Impact of Molecular Symmetry and Rigidity on the Selective Analysis of VOCs by Mid-IR Laser Spectroscopy.Analytical chemistry · 2025Article
- A Synergistic Approach Using Photoacoustic Spectroscopy and AI-Based Image Analysis for Post-Harvest Quality Assessment of Conference Pears.Molecules (Basel, Switzerland) · 2025Article
- Breath Analysis via Surface Enhanced Raman Spectroscopy.ACS sensors · 2025Review
- Measurement of Bacterial Headspaces by FT-IR Spectroscopy Reveals Distinct Volatile Organic Compound Signatures.Analytical chemistry · 2025Article
- Highly Sensitive T-Shaped Quartz Tuning Fork Based CHSensors (Basel, Switzerland) · 2024Article
- Effect of gas turbulence in quartz-enhanced photoacoustic spectroscopy: A comprehensive flow field analysis.Photoacoustics · 2024Article
- Ultra-highly sensitive dual gases detection based on photoacoustic spectroscopy by exploiting a long-wave, high-power, wide-tunable, single-longitudinal-mode solid-state laser.Light, science & applications · 2024Article
- Comb spectroscopy of COBiomedical optics express · 2024Article
- COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis.BioImpacts : BI · 2024Review
- Dual-comb optomechanical spectroscopy.Nature communications · 2023Article
- A sub-ppbv-level Acetone and Ethanol Quantum Cascade Laser Based Photoacoustic Sensor - Characterization and Multi-Component Spectra Recording in Synthetic Breath.Photoacoustics · 2023Article
- Rapid Detection of Volatile Organic Compounds by Switch-Scan Tuning of Vernier Quantum-Cascade Lasers.Analytical chemistry · 2023Article
- Dual-comb quartz-enhanced photoacoustic spectroscopy.Photoacoustics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 9 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detection and analysis of volatile compounds in exhaled breath represents an attractive tool for monitoring the metabolic status of a patient and disease diagnosis, since it is non-invasive and fast. Numerous studies have already demonstrated the benefit of breath analysis in clinical settings/applications and encouraged multidisciplinary research to reveal new insights regarding the origins, pathways, and pathophysiological roles of breath components. Many breath analysis methods are currently available to help explore these directions, ranging from mass spectrometry to laser-based spectroscopy and sensor arrays. This review presents an update of the current status of optical methods, using near and mid-infrared sources, for clinical breath gas analysis over the last decade and describes recent technological developments and their applications. The review includes: tunable diode laser absorption spectroscopy, cavity ring-down spectroscopy, integrated cavity output spectroscopy, cavity-enhanced absorption spectroscopy, photoacoustic spectroscopy, quartz-enhanced photoacoustic spectroscopy, and optical frequency comb spectroscopy. A SWOT analysis (strengths, weaknesses, opportunities, and threats) is presented that describes the laser-based techniques within the clinical framework of breath research and their appealing features for clinical use.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.