ArticleJournal of food science and technology2019
Sustainable approach for lycopene extraction from tomato processing by-product using hydrophobic eutectic solvents.
Article in Journal of food science and technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Experimental optimization of nanofiltration with a novel two-stage periodic washing mechanism for bioactive compound concentration in tomato serum.Food chemistry: X · 2026Article
- Green metabolic engineering of Synechocystis sp. PCC 6803 for efficient production and sustainable extraction of β-cryptoxanthin and zeaxanthin.Microbial cell factories · 2026Article
- Sustainable Extraction Technology of Fruit and Vegetable Residues as Novel Food Ingredients.Foods (Basel, Switzerland) · 2025Review
- Innovative Alkanediol-Based Eutectic Solvents for Extracting/Pre-Formulating Dermatologically Valuable Free Fatty Acids fromMarine drugs · 2024Article
- Green Solvents for Extraction of Natural Food Colorants from Plants: Selectivity and Stability Issues.Foods (Basel, Switzerland) · 2024Review
- NaDES Application in Cosmetic and Pharmaceutical Fields: An Overview.Gels (Basel, Switzerland) · 2024Review
- Response Surface Methodology to Optimize the Extraction of Carotenoids from Horticultural By-Products-A Systematic Review.Foods (Basel, Switzerland) · 2023Review
- Hydrophobic Deep Eutectic Solvents as Greener Substitutes for Conventional Extraction Media: Examples and Techniques.ACS omega · 2023Review
- Green Solvents: Emerging Alternatives for Carotenoid Extraction from Fruit and Vegetable By-Products.Foods (Basel, Switzerland) · 2023Review
- A Comprehensive Overview of Tomato Processing By-Product Valorization by Conventional Methods versus Emerging Technologies.Foods (Basel, Switzerland) · 2022Review
- Extraction of Lycopene from Tomato Using Hydrophobic Natural Deep Eutectic Solvents Based on Terpenes and Fatty Acids.Foods (Basel, Switzerland) · 2022Article
- Non-conventional techniques for the extraction of antioxidant compounds and lycopene from industrial tomato pomace (Food chemistry: X · 2022Article
- Long-chain alkanol-alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma.Journal of pharmaceutical analysis · 2022Article
- Sustainable Drying and Green Deep Eutectic Extraction of Carotenoids from Tomato Pomace.Foods (Basel, Switzerland) · 2022Article
- Valorization of Tomato Waste as a Source of Carotenoids.Molecules (Basel, Switzerland) · 2021Review
- Optimization of Extraction of Bioactive Compounds fromMolecules (Basel, Switzerland) · 2021Article
- Anti-Parasitic Activity of Cherry Tomato Peel Powders.Foods (Basel, Switzerland) · 2021Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Lycopene, a non-polar antioxidant compound with important effects on human health and wide commercial applications, was extracted from tomato processing wastes using innovative hydrophobic eutectic mixtures (HEMs) replacing traditional organic solvents. HEMs were prepared using DL-menthol as hydrogen-bond acceptor (HBA) and lactic acid as hydrogen-bond donor (HBD), and the ultrasound-assisted extraction (UAE) was optimized using a Box-Behnken design to evaluate extraction conditions: extraction temperature (°C), molar ratio of eutectic mixture (moles HBA: mol HBD), solvent to sample ratio (volume to mass, mL/g), and extraction time (min), with lycopene extraction yield (µg/g d.w.) as the response variable. Optimization of parameters was performed using response surface methodology, and the optimized extraction conditions were determined to be 70 °C, 8:1 mol HBA/mol HBD, 120 mL/g solvent: sample, and 10 min. The experimental optimal yield was 1446.6 µg/g, in agreement with the predicted optimal yield, indicating the validity of the model. This new technique for lycopene extraction, using a HEM as extraction solvent in replacement of hazardous organic solvents, and tomato pomace as source material, represents a viable and more sustainable approach for obtaining a high value-added bioactive compound, and can contribute towards the development of greener extraction processes.
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