ArticleJournal of epidemiology2020
Associations of Frequency of Laughter With Risk of All-Cause Mortality and Cardiovascular Disease Incidence in a General Population: Findings From the Yamagata Study.
Article in Journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 50 citations in OpenAlex.
- Laughter yoga as an enjoyable therapeutic approach for glycemic control in individuals with type 2 diabetes: A randomized controlled trial.Frontiers in endocrinology · 2023Trial
- Effects of a laughter program on body weight and mental health among Japanese people with metabolic syndrome risk factors: a randomized controlled trial.BMC geriatrics · 2022Trial
- The status of health-related quality of life among older adults with overactive bladder: a cross-sectional analysis of the Yamagata Cohort Study in Japan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Differential dose-response associations of leisure-time and non-leisure-time physical activity with perceived stress in middle-aged and older adults.Scientific reports · 2026Article
- Beyond Humor: Laughter as a Cardiovascular Stimulus.Arquivos brasileiros de cardiologia · 2026Article
- Laughing During Conversations, But Not in Response to Digital Media, Is Associated With Less Loneliness, Social Isolation, and Social Withdrawal: A Cross-Sectional Study of German Adults in 2023.Health science reports · 2025Article
- How is the Beginning and End of Frequent Laughter Associated With Changes in Loneliness Amongst Older People in Japan? A JAGES Longitudinal Study.International journal of geriatric psychiatry · 2025Article
- Frequency of Conversation, Laughter and Other Vocalising Opportunities in Daily Life and Maximum Tongue Pressure: The Goto Longevity Study.Journal of oral rehabilitation · 2025Article
- The relationship between gratitude and presenteeism among workers: a cross-sectional study.Nagoya journal of medical science · 2025Article
- Dry eye disease and psychosomatics-benefits of mind-body therapy for dry eye disease.Frontiers in medicine · 2025Review
- Does online communication mitigate the association between a decrease in face-to-face communication and laughter during the COVID-19 pandemic? A cross-sectional study from JACSIS study.Preventive medicine reports · 2023Article
- Subjective Happiness, Frequency of Laughter, and Hypertension: A Cross-Sectional Study Based on the Japan Gerontological Evaluation Study (JAGES).International journal of environmental research and public health · 2023Article
- The Association between Laughter and Functional Dyspepsia in a Young Japanese Population.International journal of environmental research and public health · 2022Article
- Observational
- Association between Laughter and Lifestyle Diseases after the Great East Japan Earthquake: The Fukushima Health Management Survey.International journal of environmental research and public health · 2021Article
- Association between milk and yogurt intake and mortality: a community-based cohort study (Yamagata study).BMC nutrition · 2021Article
- Association between frequency of laughter and oral health among community-dwelling older adults: a population-based cross-sectional study in Japan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Does Laughter Predict Onset of Functional Disability and Mortality Among Older Japanese Adults? The JAGES Prospective Cohort Study.Journal of epidemiology · 2021Article
- The Smiles of Older People through Recreational Activities: Relationship between Smiles and Joy.International journal of environmental research and public health · 2021Article
- Does variety of social interactions associate with frequency of laughter among older people? The JAGES cross-sectional study.BMJ open · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPositive and negative psychological factors are associated with mortality and cardiovascular disease. This study prospectively investigated associations of daily frequency of laughter with mortality and cardiovascular disease in a community-based population.
methodsThis study included 17,152 subjects ≥40 years old who participated in an annual health check in Yamagata Prefecture. Self-reported daily frequency of laughter was grouped into three categories (≥1/week; ≥1/month but <1/week; <1/month). Associations of daily frequency of laughter with increase in all-cause mortality and cardiovascular disease incidence were determined using Cox proportional hazards modeling.
resultsDuring follow-up (median, 5.4 years), 257 subjects died and 138 subjects experienced cardiovascular events. Kaplan-Meier analysis revealed that all-cause mortality and cardiovascular disease incidence were significantly higher among subjects with a low frequency of laughter (log-rank P < 0.01). Cox proportional hazard model analysis adjusted for age, gender, hypertension, smoking, and alcohol drinking status showed that risk of all-cause mortality was significantly higher in subjects who laughed <1/month than in subjects who laughed ≥1/week (hazard ratio [HR] 1.95; 95% confidence interval [CI], 1.16-3.09). Similarly, risk of cardiovascular events was higher in subjects who laughed ≥1/month but <1/week than in subjects who laughed ≥1/week (HR 1.62; 95% CI, 1.07-2.40).
conclusionDaily frequency of laughter represents an independent risk factor for all-cause mortality and cardiovascular disease in a Japanese general population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.