ArticleCell2019
A Jasmonate Signaling Network Activates Root Stem Cells and Promotes Regeneration.
Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers.
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Who cites it
165 citing papers in PubMed, 352 citations in OpenAlex.
- Cyclin' Through the Root: Developmental Control of Cell Cycle Progression in theAnnual review of cell and developmental biology · 2026Review
- The genome of Thesium ramosoides (Santalales) reveals evolutionary dynamics associated with parasitism and alpine adaptation.Plant communications · 2026Article
- Asparagine Synthetase 1 regulates rice seminal root elongation via jasmonic acid metabolism.Plant cell reports · 2026Article
- Endophytic Flavobacterium promotes root hair development and enhances drought tolerance via an ERF-CEP5 hormonal regulatory module.Nature plants · 2026Article
- Comparative Wound Healing Processes in Plants and Animals: Bioinspired Strategies for Advancing Regenerative Medicine.International journal of molecular sciences · 2026Review
- The Arabidopsis ARF3-AIP1/2-SAP18 module specifies the root stem cell niche in response to auxin.The Plant cell · 2026Article
- Histone deacetylases and cell-cycle regulators orchestrate cell-identity transitions during Arabidopsis root regeneration.Molecular plant · 2026Article
- Overexpression of TkMYC2 enhances drought tolerance and rubber-producing capacity in transgenic Taraxacum kok-saghyz.Planta · 2026Article
- Multi-omics analysis reveals molecular mechanisms of maize responses to hexavalent chromium toxicity.BMC plant biology · 2026Article
- Dedifferentiation of Plant Cells: A Term Covering Multiple Pathways?Plants (Basel, Switzerland) · 2026Article
- GhZAT11 triggers wound-activated bud growth by accelerating sugar transport and cell division.Nature plants · 2026Article
- The role of jasmonates in plant root growth and development.Frontiers in plant science · 2026Review
- Cytokinin-supplemented medium drivesFrontiers in plant science · 2026Article
- The LFR-SWI/SNF complex: A chromatin wrench safeguarding cellular quiescence in theProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Robustness in jasmonate signaling: mechanisms of concerted regulation and implications for crop improvement.aBIOTECH · 2025Review
- Auxin transport positions stem cells in the vascular cambium during normal development and regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Tetraspanin OsTET8 acts as a negative regulator of root development in rice.Rice (New York, N.Y.) · 2025Article
- Rational design of induced regeneration via somatic embryogenesis in the absence of exogenous phytohormones.The Plant cell · 2025Article
- Mechanism and Application of Developmental Factors in Plant Genetic Transformation.International journal of molecular sciences · 2025Review
- Jasmonate primes plant responses to extracellular ATP.The Plant journal : for cell and molecular biology · 2025Article
105 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants are sessile and have to cope with environmentally induced damage through modification of growth and defense pathways. How tissue regeneration is triggered in such responses and whether this involves stem cell activation is an open question. The stress hormone jasmonate (JA) plays well-established roles in wounding and defense responses. JA also affects growth, which is hitherto interpreted as a trade-off between growth and defense. Here, we describe a molecular network triggered by wound-induced JA that promotes stem cell activation and regeneration. JA regulates organizer cell activity in the root stem cell niche through the RBR-SCR network and stress response protein ERF115. Moreover, JA-induced ERF109 transcription stimulates CYCD6;1 expression, functions upstream of ERF115, and promotes regeneration. Soil penetration and response to nematode herbivory induce and require this JA-mediated regeneration response. Therefore, the JA tissue damage response pathway induces stem cell activation and regeneration and activates growth after environmental stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.