ArticleGM crops & food2019
Unintended effects of transgenic rice revealed by transcriptome and metabolism.
Article in GM crops & food, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Evaluation of the Unintended Effects ofBiomolecules · 2025Article
- Transcriptome and nutritional composition analysis of stacked transgenic maize with insect resistance and herbicide tolerance.GM crops & food · 2025Article
- Genetically modified soybean lines exhibit less transcriptomic variation compared to natural varieties.GM crops & food · 2023Article
- Effects of stacking breeding on the methylome and transcriptome profile of transgenic rice with glyphosate tolerance.Planta · 2023Article
- Comparison of the Phenotypic Performance, Molecular Diversity, and Proteomics in Transgenic Rice.Plants (Basel, Switzerland) · 2022Article
- Investigation of Possible Changes Induced by RNA Silencing in Some Leaf Metabolites of Transgenic Sugar Beet Events.Food chemistry. Molecular sciences · 2022Article
- Transcriptomic Analysis of Mature Transgenic Poplar Expressing the Transcription FactorFrontiers in bioengineering and biotechnology · 2022Article
- Metabolic Analysis RevealsMetabolites · 2021Article
- Evaluation on reprogramed biological processes in transgenic maize varieties using transcriptomics and metabolomics.Scientific reports · 2021Article
- Plant breeding involving genetic engineering does not result in unacceptable unintended effects in rice relative to conventional cross-breeding.The Plant journal : for cell and molecular biology · 2020Article
- Exogenous Cry1Ab/c Protein Recruits Different Endogenous Proteins for Its Function in Plant Growth and Development.Frontiers in bioengineering and biotechnology · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetically modified (GM) organisms have been developed for decades. However, unintended effects are the main concerns of safety assessment that needs to be carefully investigated. Here, eight varieties of GM rice that were developed in China were selected to assess the unintended effects through transcriptome and metabolism. There are 2892-8758 differentially expressed genes (DEGs) and 7-50 metabolites at significant level between GM varieties and their isogenic counterparts, which were far fewer than that between traditional rice varieties. The function enrichment analysis showed altered transcription in stress-related pathway and starch and sucrose metabolism. DEGs shared among eight GM samples constitute less than 1% of the genes in the genome, and none of them is reported more than four times. The insertion effect on the nearby gene expression and the associated metabolism is only restricted to 50 genes. All the results provide a comprehensive analysis of unintended effects and indication of difference in Chinese transgenic rice based on their backgrounds, transformation, and insertion elements.
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Registered trials
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