ArticleAddiction (Abingdon, England)2019
Structural brain characteristics of anabolic-androgenic steroid dependence in men.
Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Anabolic-androgenic steroid use disorder: case for recognition as a substance use disorder with specific diagnostic criteria.The British journal of psychiatry : the journal of mental science · 2026Review
- Psychological traits associated with anabolic androgenic steroid use and dependence: an exploratory cross-sectional study among female athletes.BMC women's health · 2025Article
- Relationship Between Anabolic-Androgenic Steroid Use, Aggression, and Narcissism in Male Bodybuilders.Medicina (Kaunas, Lithuania) · 2025Article
- A study of long-term supraphysiologic-dose anabolic-androgenic steroid use on cognitive function in middle-aged men.The American journal of drug and alcohol abuse · 2024Article
- Exploring Anabolic Androgenic Steroid Use Among Cisgender Gay, Bisexual, and Queer Men.JAMA network open · 2024Article
- Supraphysiological testosterone levels from anabolic steroid use and reduced sensitivity to negative facial expressions in men.Psychopharmacology · 2024Article
- Misadventures in Toxicology: Concentration Matters for Testosterone-Induced Neurotoxicity.Toxics · 2023Article
- The Uses of Anabolic Androgenic Steroids Among Athletes; Its Positive and Negative Aspects- A Literature Review.Journal of multidisciplinary healthcare · 2023Review
- Performance-Enhancing Substance Use and Intimate Partner Violence: A Prospective Cohort Study.Journal of interpersonal violence · 2022Article
- Performance-Enhancing Substance Use and Sexual Risk Behaviors among U.S. Men: Results from a Prospective Cohort Study.Journal of sex research · 2022Article
- ADHD symptoms and use of anabolic androgenic steroids among male weightlifters.Scientific reports · 2022Article
- Generating evidence on the use of Image and performance enhancing drugs in the UK: results from a scoping review and expert consultation by the Anabolic Steroid UK network.Harm reduction journal · 2021Article
- On the role of sex steroids in biological functions by classical and non-classical pathways. An update.Frontiers in neuroendocrinology · 2021Review
- Aggression and Psychological Distress in Male and Female Anabolic-Androgenic Steroid Users: A Multigroup Latent Class Analysis.Frontiers in psychiatry · 2021Article
- Article
- The Anabolic Androgenic Steroid Treatment Gap: A National Study of Substance Use Disorder Treatment.Substance abuse : research and treatment · 2020Article
- Structural brain characteristics of anabolic-androgenic steroid dependence in men.Addiction (Abingdon, England) · 2019Article
- Neuropsychiatric and Behavioral Involvement in AAS Abusers. A Literature Review.Medicina (Kaunas, Lithuania) · 2019Review
- The Impact of Doping on Cognitive Abilities and Emotional Regulation in Elite Athletes -A Neurocognitive Perspective.Current health sciences journalReview
Corrections and comments
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5 authors.
Funding
Abstract
aimTo identify differences in brain morphology between dependent and non-dependent male anabolic-androgenic steroid (AAS) users.
designThis study used cross-sectional data from a longitudinal study on male weightlifters.
participantsOslo University Hospital, Norway.
settingEighty-one AAS users were divided into two groups; AAS-dependent (n = 43) and AAS-non-dependent (n = 38). MEASUREMENTS: Neuroanatomical volumes and cerebral cortical thickness were estimated based on magnetic resonance imaging (MRI) using FreeSurfer. Background and health information were obtained using a semi-structured interview. AAS-dependence was evaluated in a standardized clinical interview using a version of the Structured Clinical Interview for DSM-IV, adapted to apply to AAS-dependence.
findingsCompared with non-dependent users, dependent users had significantly thinner cortex in three clusters of the right hemisphere and in five clusters of the left hemisphere, including frontal, temporal, parietal and occipital regions. Profound differences were seen in frontal regions (left pars orbitalis, cluster-wise P < 0.001, right superior frontal, cluster-wise P < 0.001), as has been observed in other dependencies. Group differences were also seen when excluding participants with previous or current non-AAS drug abuse (left pre-central, cluster-wise P < 0.001, left pars orbitalis, cluster-wise P = 0.010).
conclusionMale dependent anabolic-androgenic steroid users appear to have thinner cortex in widespread regions, specifically in pre-frontal areas involved in inhibitory control and emotional regulation, compared with non-dependent anabolic-androgenic steroid users.
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