A Fluorescent Flavonoid for Lysosome Imaging: the Effect of Substituents on Selectivity and Optical Properties.

Keti Assor Bertman, Chathura S Abeywickrama, Ashley Ingle, Leah P Shriver, Michael Konopka, Yi Pang

Abstract read

In one paragraph

Article in Journal of fluorescence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

0.6field-weighted citation impact, top 34% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

Binding interactions of hydrophobically-modified flavonols with β-glucosidase: fluorescence spectroscopy and molecular modelling study.RSC advances · 2023
Article
Advancements in Biosensors Based on the Assembles of Small Organic Molecules and Peptides.Biosensors · 2023
Review
Simultaneous Visualization of Mitochondria and Lysosome by a Single Cyanine Dye: The Impact of the Donor Group (-NRJournal of fluorescence · 2021
Article
Synthesis of a far-red emitting flavonoid-based lysosome marker for live cell imaging applications.Bioorganic chemistry · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Keti Assor BertmanDepartment of Chemistry, University of Akron, Akron, OH, 44325, USA.

Chathura S AbeywickramaDepartment of Chemistry, University of Akron, Akron, OH, 44325, USA.

Ashley IngleDepartment of Chemistry, University of Akron, Akron, OH, 44325, USA.

Leah P ShriverDepartment of Chemistry, University of Akron, Akron, OH, 44325, USA.

Michael KonopkaDepartment of Chemistry, University of Akron, Akron, OH, 44325, USA.

Yi PangDepartment of Chemistry, University of Akron, Akron, OH, 44325, USA. yp5@uakron.edu.

University of Akron · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysosome selective bright orange-red emitting flavonoid (2) was synthesized by attaching a strong donor (NPh

Indexed as

Optical PhenomenaCell LineCell SurvivalFlavonoidsFluorescent DyesHumansLysosomesOptical ImagingTemperatureFlavonoidsFluorescent DyesExcited state intra-molecular proton transfer (ESIPT)FlavonoidIntra-molecular charge transfer (ICT)Lysosome probesStokes shiftSubstituent effect

Identifiers

PMID30955153

DOI10.1007/s10895-019-02371-7

OpenAlexW2931005058

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.