ArticleMolecular diversity2020
Amine-functionalized graphene oxide nanosheets (AFGONs): an efficient bifunctional catalyst for selective formation of 1,4-dihydropyridines, acridinediones and polyhydroquinolines.
Article in Molecular diversity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- GO/APTES-mediated bifunctional CuFeRSC advances · 2026Article
- Copper ions-coordinated galacturonic acid-modified UiO-66-NHScientific reports · 2026Article
- Graphene oxide immobilized 2-morpholinoethanamine as a versatile acid-base catalyst for synthesis of some heterocyclic compounds and molecular docking study.Scientific reports · 2023Article
- Construction of 1,4-Dihydropyridines: The Evolution of C4 Source.Topics in current chemistry (Cham) · 2023Review
- Ultrasound-Promoted preparation and application of novel bifunctional core/shell FeScientific reports · 2023Article
- β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one.RSC advances · 2023Article
- Article
- Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide-Fucoidan in the Synthesis of 1,4-Dihydropyridines and Polyhydroquinolines.ChemistryOpen · 2021Article
- Urease: a highly efficient biocatalyst for synthesis of polyhydroquinolines and polyhydroacridines from the ammonia formed in situ.Molecular diversity · 2021Article
- β-Cyclodextrin: a supramolecular catalyst for metal-free approach towards the synthesis of 2-amino-4,6-diphenylnicotinonitriles and 2,3-dihydroquinazolin-4(1RSC advances · 2021Article
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3 authors.
Funding
Abstract
We report here selective formation of functionalized 1,4-dihydropyridines (DHP), acridinediones and polyhydroquinolines in high yields using amine-functionalized graphene oxide nanosheets (AFGONs) as the bifunctional catalyst. The method overcomes the limitations of previous protocols affording a mixture of DHP and pyridine derivatives using graphene oxide as the catalyst. The mild reaction conditions are found compatible with a wide range of functional groups. It is presumed that a cooperative effect between the acidic and basic functionalities present in AFGONs may have exerted high catalytic efficiency as well as prevented further oxidation to pyridine derivatives. A plausible mechanism is proposed on the basis of some control experiments. The reactions can be scaled up conveniently, and the catalyst can be recycled for five consecutive runs without loss of its activity.
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