ArticleTropical animal health and production2019
Genetic analysis of bovine viral diarrhea virus in pre-weaned native Korean calves.
Article in Tropical animal health and production, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Bovine Viral Diarrhoea Virus Across Asia: A Systematic Review and Meta-Analysis of Prevalence in Cattle Population Between 2000 and 2025.Veterinary medicine and science · 2026Pooled it
- Prevalence of bovine viral diarrhea virus in cattle between 2010 and 2021: A global systematic review and meta-analysis.Frontiers in veterinary science · 2022Pooled it
- Molecular detection and genotyping of bovine viral diarrhea virus in four provinces of China.Archives of virology · 2025Article
- Molecular Epidemiology and Control Strategies for BVDV: A Global Systematic Review From 2000 to 2025.Veterinary medicine international · 2025Review
- Laboratory investigation of causes of bovine abortion and stillbirth in the Republic of Korea, 2014-2020.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Bovine viral diarrhea virus (BVDV), a prominent viral pathogen worldwide, causes substantial economic losses in the cattle industry. BVDV comprises two recognized species, BVDV-1 and BVDV-2, and at least 21 subtypes (1a-1u) for BVDV-1 and four subtypes (2a-2d) for BVDV-2 based on its 5'-untranslated region. This study aimed at investigating the prevalence and genetic analysis of BVDV in calf feces in the Republic of Korea (ROK). We collected fecal samples from 635 pre-weaned native Korean calves aged 1-60 days, regardless of diarrhea, and subjected them to RT-PCR and phylogenetic analysis. Thirty-five (5.5%) of the 635 samples were positive for BVDV infection. BVDV was detected in 20, 10, and 5 calves aged 1-20 days, 21-40 days, and 41-60 days, respectively. BVDV was the most frequent in 17 normal feces, followed by 16 diarrheic feces, and 2 hemorrhagic feces. Phylogenetic analysis revealed that 25 samples belonged to BVDV-1b; 1 sample, BVDV-1c; and 9 samples, BVDV-2a. Moreover, the BVDV-1b and BVDV-2a isolates showed genetic variations. BVDV-1b was detected in diarrheic, hemorrhagic, and normal fecal samples. Thus, BVDV-1b is the most prevalent in calves and causes enteric disease with differing severity. BVDV-1c was newly identified in diarrheic calves. Further studies are warranted to elucidate the pathogenesis of BVDV-1c infection and its clinical manifestations. Our results indicate that effective vaccines and control programs against BVDV are required in the ROK.
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