SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019
Effect of sarcopenia on clinical outcomes following digestive carcinoma surgery: a meta-analysis.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Effects of Sarcopenia on Patient Outcomes in Gastrointestinal Cancer: An Umbrella Review of Published Meta-Analyses.Journal of gastrointestinal cancer · 2025Pooled it
- Predictive value of preoperative handgrip strength on postoperative outcomes in patients with gastrointestinal tumors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Skeletal Muscle Change During Neoadjuvant Therapy and Its Impact on Prognosis in Patients With Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2022Pooled it
- Sarcopenia predicts worse postoperative outcomes and decreased survival rates in patients with colorectal cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Sarcopenia and adverse health-related outcomes: An umbrella review of meta-analyses of observational studies.Cancer medicine · 2020Pooled it
- Sarcopenia in gallbladder perforation: a radiological comparison study.Abdominal radiology (New York) · 2026Article
- Investigating the effects of olanzapine on appetite and weight in patients with cancer in a systematic review.Discover oncology · 2026Review
- Systemic Inflammation and Disruption of the Local Microenvironment Compromise Muscle Regeneration: Critical Pathogenesis of Autoimmune-Associated Sarcopenia.Interactive journal of medical research · 2025Article
- Effects of the Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls score on postoperative clinical outcomes following colorectal cancer surgery: a retrospective study.European journal of clinical nutrition · 2025Article
- Preoperative body composition metrics as predictors for outcomes in colorectal cancer surgeries.Annals of medicine and surgery (2012) · 2025Article
- The predictive values of sarcopenia screening tools in preoperative elderly patients with colorectal cancer: applying the diagnostic criteria of EWGSOP2 and AWGS2019.BMC geriatrics · 2025Article
- Changes in Skeletal Muscle Mass in the First 3 Months Following Gastrointestinal Cancer Surgery: A Prospective Study.Annals of surgical oncology · 2024Article
- Association of Perioperative Skeletal Muscle Index Change With Outcome in Colorectal Cancer Patients.Journal of cachexia, sarcopenia and muscle · 2024Article
- Association of metabolic syndrome and frailty with postoperative complications in older gastric cancer patients: A body composition perspective.Cancer medicine · 2024Observational
- Sarcopenia as a Prognostic Factor and Multimodal Interventions in Breast Cancer.International journal of general medicine · 2024Article
- Postoperative muscle loss, protein intake, physical activity and outcome associations.The British journal of surgery · 2023Observational
- The impact of sarcopenia on the postoperative outcome in colorectal cancer surgery.Medicine and pharmacy reports · 2023Review
- Association between CT-Based Preoperative Sarcopenia and Outcomes in Patients That Underwent Liver Resections.Cancers · 2022Article
- Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study.Journal of nutrition and metabolism · 2022Article
- Paradigm shift in gastrointestinal surgery - combating sarcopenia with prehabilitation: Multimodal review of clinical and scientific data.World journal of gastrointestinal surgery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe effect of sarcopenia on digestive carcinoma surgery outcomes is controversial. We aimed to assess the effect of sarcopenia defined by the European Working Group on Sarcopenia in Older People (EWGSOP) or the Asian Working Group for Sarcopenia (AWGS) on outcomes following digestive carcinoma surgery.
methodsEligible studies were searched from PubMed, EMBASE and other databases from inception to April 2018. We conducted a meta-analysis to estimate the risk ratios or mean differences of outcomes in the sarcopenia group versus the non-sarcopenia group. Stratified analyses and sensitivity analyses were performed.
resultsWe included 11 cohort studies, with a sarcopenia prevalence ranging from 11.6 to 33.0%. Sarcopenia was associated with an increased risk of total complications (RR = 1.87, P < 0.00001), major complications (RR = 2.45, P = 0.002), re-admissions (RR = 2.53,P < 0.0001), infections (RR = 2.23, P = 0.09), severe infections (RR = 2.96, P = 0.04), 30-day mortality (RR = 3.36, P = 0.001), longer hospital stay (MD = 4.61, P = 0.001) and increased hospitalization expenditures (SMD = 0.25, P = 0.02). Sarcopenia differentially affected outcomes when stratified, and the results were stable.
conclusionsSarcopenia defined by the EWGSOP or AWGS Consensus was a high-risk factor for digestive carcinoma surgery outcomes. Different tumour site and muscle mass measurements are the sources of heterogeneity. More high-quality studies are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.