Evidence map›Paper›PMID 30954661›Full record

ArticleJournal of the neurological sciences2019

Tremor in normal adults: A population-based study of 1158 adults in the Faroe Islands.

Elan D Louis, Monica Ferrer, Eina H Eliasen, Shahin Gaini, Maria Skaalum Petersen

Open access · greenAbstract read
In one paragraph

Article in Journal of the neurological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Tremor Following Guillain Barré Syndrome.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024
    Article
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Elan D LouisDepartment of Neurology, Yale School of Medicine, Yale University, New Haven, CT, USA; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT, USA; Center for Neuroepidemiology and Clinical Neurological Research, Yale School of Medicine, Yale University, New Haven, CT, USA. Electronic address: elan.louis@yale.edu.
Monica FerrerDepartment of Neurology, Yale School of Medicine, Yale University, New Haven, CT, USA.
Eina H EliasenDepartment of Occupational Medicine and Public Health, The Faroese Hospital System, Tórshavn, Faroe Islands.
Shahin GainiInfectious Diseases Division, National Hospital Faroe Islands, Tórshavn, Faroe Islands; Department of Infectious Diseases, Odense University Hospital/University of Southern Denmark, Odense, Denmark; Centre for Health Science, Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands.
Maria Skaalum PetersenDepartment of Occupational Medicine and Public Health, The Faroese Hospital System, Tórshavn, Faroe Islands; Centre for Health Science, Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands.
University of the Faroe Islands · FOYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMORR01NS039422 · NINDS · YALE UNIVERSITY · PI LOUIS, ELAN D · 2000 to 2013
$7.7M
Identification of Susceptibility Genes for Essential TremorR01NS073872 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLARK, LORRAINE N, LOUIS, ELAN D · 2011 to 2019
$7.4M
Environmental Epidemiology of Essential TremorR01NS094607 · NINDS · YALE UNIVERSITY · PI LOUIS, ELAN D · 2016 to 2020
$3.9M
NCATS NIH HHS UL1 TR001863NINDS NIH HHS R01 NS039422NINDS NIH HHS R01 NS073872NINDS NIH HHS R01 NS094607
6 · The paper itself

Abstract

There are virtually no population-based data on tremor in normal individuals. Using a population-based sample of 1158 normal adults ages 40-98 years in the Faroe Islands, we characterized the extent of normal action tremor across age and gender strata. Participants drew two Archimedes spirals with each hand, and tremor was systematically quantified by a senior movement disorder neurologist using a reliable and valid ordinal rating scale (ratings = 0-3). Tremor was nearly universal - 1145 (98.9%) participants had a total mean spiral score > 0. Older age was associated with more tremor (p < .001) and spiral scores were higher in males than females (p < .001). The proportion of individuals with a spiral rating ≥ 1.5 (i.e., more than mild tremor) was low (1.8% - 8.5%); however, this value reached 19.6% in left-hand spirals of males ≥70 years old. In this population-based study of more than one thousand normal adults, the vast bulk (i.e., 98.9%) had tremor on spiral drawing. In general, the tremor was mild. The proportion of individuals with tremor above the mild range varied across age and gender strata. These extensive data may be used as a gold standard for defining normal levels of tremor within adult populations.

Indexed as

Population SurveillanceAdultAgedAged, 80 and overDenmarkFemaleHumansMaleMiddle AgedTremorEpidemiologyEssential tremorHandwritingNormalPopulationTremor

Identifiers

PMID30954661
PMCPMC6475466
OpenAlexW2922982008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.