Evidence map›Paper›PMID 30954496›Full record

ArticleSexual medicine2019

Provoked Vestibulodynia in Women with Pelvic Pain.

Carol Bao, Heather Noga, Catherine Allaire, Christina Williams, Mohamed A Bedaiwy, Leslie A Sadownik, Lori A Brotto, Kelly B Smith, Paul J Yong

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sexual medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02911090 (Endometriosis Pelvic Pain Interdisciplinary Cohort), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02911090 enrolling by invitationnot on this map

Endometriosis Pelvic Pain Interdisciplinary Cohort (EPPIC) Data Registry

Typeobservational_patient_registrySponsorBC Women's Hospital & Health CentreRan2016 to 2028Enrolled5,000ConditionsEndometriosisArmsData Registry
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carol BaoBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, British Columbia, Canada.
Heather NogaWomen's Health Research Institute, Vancouver, British Columbia, Canada.
Catherine AllaireBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, British Columbia, Canada; Women's Health Research Institute, Vancouver, British Columbia, Canada; Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.
Christina WilliamsBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, British Columbia, Canada; Women's Health Research Institute, Vancouver, British Columbia, Canada; Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.
Mohamed A BedaiwyBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, British Columbia, Canada; Women's Health Research Institute, Vancouver, British Columbia, Canada; Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.
Leslie A SadownikDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada; BC Centre for Vulvar Health, Vancouver, British Columbia, Canada.
Lori A BrottoWomen's Health Research Institute, Vancouver, British Columbia, Canada; Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada; BC Centre for Vulvar Health, Vancouver, British Columbia, Canada.
Kelly B SmithBC Centre for Vulvar Health, Vancouver, British Columbia, Canada.
Paul J YongBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, British Columbia, Canada; Women's Health Research Institute, Vancouver, British Columbia, Canada; Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada; BC Centre for Vulvar Health, Vancouver, British Columbia, Canada. Electronic address: paul.yong@vch.ca.
Women's Health Research Institute · CAUniversity of British Columbia · CABritish Columbia Centre of Excellence for Women's Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPelvic pain and vulvar pain are common conditions in women. In this study, we sought to characterize the clinical picture of patients with concurrent pelvic pain and provoked vestibulodynia (PVD).

aimTo analyze the association between sexual/clinical characteristics and a diagnosis of PVD among women with pelvic pain.

methodsCross-sectional analysis of a prospective registry at a tertiary referral center for pelvic pain and endometriosis, involving consecutive non-menopausal sexually active patients 18-49 years-old seen by a single gynecologist from January 2016-December 2017. The sample was divided into 2 groups: pelvic pain with PVD; and pelvic pain alone (without PVD).

main outcome measuresSuperficial dyspareunia and deep dyspareunia on a 11-point numeric rating scale, and the sexual quality-of-life subscale of the Endometriosis Health Profile-30 (0-100%).

resultsThere were 129 patients that met study criteria: one third with pelvic pain and PVD (n = 42) and two-thirds with pelvic pain alone (without PVD) (n = 87). Women with pelvic pain and PVD had significantly more severe superficial dyspareunia ≥7/10 (OR = 12.00 (4.48-32.16), P < .001), more severe deep dyspareunia ≥7/10 (OR = 4.08 (1.83-9.10), P = .001), and poorer sexual quality of life (Endometriosis Health Profile-30 ≥50%) (OR = 4.39 (1.67-11.57), P = .002), compared with the group with pelvic pain alone. Women with pelvic pain and PVD also had more anxiety, depression, and catastrophizing, more frequent tenderness of the bladder and pelvic floor, and more common diagnosis of painful bladder syndrome. On the other hand, there were no significant differences between the 2 groups in terms of dysmenorrhea, chronic pelvic pain, abdominal wall allodynia, positive Carnett test for abdominal wall pain, functional quality of life, endometriosis, and irritable bowel syndrome.

conclusionsIn the pelvic pain population, PVD may be associated with more negative impact on dyspareunia, sexual quality of life, and bladder/pelvic floor function, but it may not significantly impact abdominopelvic pain or day-to-day function in general. Bao C, Noga H, Allaire C, et al. Provoked Vestibulodynia in Women with Pelvic Pain. Sex Med 2019;7:227-234.

Indexed as

DyspareuniaEndometriosisPainful Bladder SyndromePelvic FloorPelvic PainVestibulodyniaVulvodynia

Identifiers

PMID30954496
PMCPMC6523038
OpenAlexW2926176371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.