ArticleBiological research2019
Molecular cloning and subcellular localization of six HDACs and their roles in response to salt and drought stress in kenaf (Hibiscus cannabinus L.).
Article in Biological research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Roles and Mechanisms of Histone Deacetylases in Plant Abiotic Stress Responses.Antioxidants (Basel, Switzerland) · 2026Review
- Interactions Between Plant Proteins and Gut Microbiota as Determinants of Intestinal Health.Microorganisms · 2026Review
- Stabilization of the MAPK-Epigenetic Signaling Axis Underlies the Protective Effect of Thyme Oil Against Cadmium Stress in Root Meristem Cells ofInternational journal of molecular sciences · 2025Article
- Research advances in epigenetic modifications and post-translational modifications in endothelial-mesenchymal transition.Epigenetics & chromatin · 2025Review
- Histone H3K27 acetylation mediated by KAT8 maintains antiviral trained immunity in shrimp induced by inactivated white spot syndrome virus.Communications biology · 2025Article
- Physiological and Transcriptome Analysis Reveal the Underlying Mechanism of Salicylic Acid-Alleviated Drought Stress in Kenaf (Life (Basel, Switzerland) · 2025Article
- Transcriptome analysis revealed key genes and pathways related to cadmium tolerance and accumulation in coix (Frontiers in plant science · 2025Article
- Genome-wide mapping of main histone modifications and coordination regulation of metabolic genes under salt stress in pea (Horticulture research · 2024Article
- Insights into the Epigenetic Basis of Plant Salt Tolerance.International journal of molecular sciences · 2024Review
- Genome-Wide Analysis of the Histone Modification Gene (Plants (Basel, Switzerland) · 2024Article
- Genome-wide identification of bHLH transcription factors in Kenaf (Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Genome-wide identification and expression analysis of histone deacetylase and histone acetyltransferase genes in response to drought in poplars.BMC genomics · 2024Article
- Integrated physiological and metabolomic responses reveal mechanisms of Cd tolerance and detoxification in kenaf (Frontiers in plant science · 2024Article
- Epigenetic Regulation in Heterosis and Environmental Stress: The Challenge of Producing Hybrid Epigenomes to Face Climate Change.Epigenomes · 2023Review
- Article
- Salt Stress Induces Changes in Physiological Characteristics, Bioactive Constituents, and Antioxidants in Kenaf (Antioxidants (Basel, Switzerland) · 2022Article
- Integrated Methylome and Transcriptome Analysis Provides Insights into the DNA Methylation Underlying the Mechanism of Cytoplasmic Male Sterility in Kenaf (International journal of molecular sciences · 2022Article
- Uncovering the Epigenetic Marks Involved in Mediating Salt Stress Tolerance in Plants.Frontiers in genetics · 2022Review
- Review
- H3K14 hyperacetylation‑mediated c‑Myc binding to the miR‑30a‑5p gene promoter under hypoxia postconditioning protects senescent cardiomyocytes from hypoxia/reoxygenation injury.Molecular medicine reports · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHistone acetylation is an important epigenetic modification that regulates gene activity in response to stress. Histone acetylation levels are reversibly regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). The imperative roles of HDACs in gene transcription, transcriptional regulation, growth and responses to stressful environment have been widely investigated in Arabidopsis. However, data regarding HDACs in kenaf crop has not been disclosed yet.
resultsIn this study, six HDACs genes (HcHDA2, HcHDA6, HcHDA8, HcHDA9, HcHDA19, and HcSRT2) were isolated and characterized. Phylogenetic tree revealed that these HcHDACs shared high degree of sequence homology with those of Gossypium arboreum. Subcellular localization analysis showed that GFP-tagged HcHDA2 and HcHDA8 were predominantly localized in the nucleus, HcHDA6 and HcHDA19 in nucleus and cytosol. The HcHDA9 was found in both nucleus and plasma membranes. Real-time quantitative PCR showed that the six HcHDACs genes were expressed with distinct expression patterns across plant tissues. Furthermore, we determined differential accumulation of HcHDACs transcripts under salt and drought treatments, indicating that these enzymes may participate in the biological process under stress in kenaf. Finally, we showed that the levels of histone H3 and H4 acetylation were modulated by salt and drought stress in kenaf.
conclusionsWe have isolated and characterized six HDACs genes from kenaf. These data showed that HDACs are imperative players for growth and development as well abiotic stress responses in kenaf.
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