Evidence map›Paper›PMID 30953502›Full record

ArticleBMC health services research2019

Explaining patient delay in healthcare seeking and loss to diagnostic follow-up among patients with presumptive tuberculosis in Tanzania: a mixed-methods study.

Grace Mhalu, Mitchell G Weiss, Jerry Hella, Francis Mhimbira, Enos Mahongo, Christian Schindler, Klaus Reither, Lukas Fenner, Elisabeth Zemp, Sonja Merten

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC health services research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Grace MhaluIfakara Health Institute, Dar es Salaam and Bagamoyo, Tanzania. gmhalu@ihi.or.tz.ORCID http://orcid.org/0000-0002-0417-3027
Mitchell G WeissSwiss Tropical and Public Health Institute, Basel, Switzerland.
Jerry HellaIfakara Health Institute, Dar es Salaam and Bagamoyo, Tanzania.
Francis MhimbiraIfakara Health Institute, Dar es Salaam and Bagamoyo, Tanzania.
Enos MahongoIfakara Health Institute, Dar es Salaam and Bagamoyo, Tanzania.
Christian SchindlerSwiss Tropical and Public Health Institute, Basel, Switzerland.
Klaus ReitherSwiss Tropical and Public Health Institute, Basel, Switzerland.
Lukas FennerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Elisabeth ZempSwiss Tropical and Public Health Institute, Basel, Switzerland.
Sonja MertenSwiss Tropical and Public Health Institute, Basel, Switzerland.
Swiss Tropical and Public Health Institute · CHIfakara Health Institute · TZUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelay in healthcare seeking and loss to diagnostic follow-up (LDFU) contribute to substantial increase in tuberculosis (TB) morbidity and mortality. We examined factors, including perceived causes and prior help seeking, contributing to delay and LDFU during referral to a TB clinic among patients with presumptive TB initially seeking help at the pharmacies in Dar es Salaam Tanzania.

methodsIn a TB clinic, a semi-structured interview based on the explanatory model interview catalogue (EMIC) framework for cultural epidemiology was administered to presumptive TB patients enrolled at pharmacies during an intervention study. We assessed delay in seeking care at any medical care provider for a period of ≥3 weeks after the onset of symptoms, LDFU during referral (not reaching the TB clinic), and LDFU for three required TB clinic visits among the presumptive and confirmed TB patients. Logistic regression models were used to assess factors associated with delay and LDFU.

resultsAmong 136 interviewed patients, 86 (63.2%) were LDFU from pharmacies and TB clinic while 50 (36.8%) were non-LDFU. Out of 136 patients 88 (64.7%) delayed seeking care, of whom 59 (67%) were females. Among the 86 (63.2%) patients in LDFU group, 62 (72.1%) delayed seeking care, while among the 50 (36.8%) non-LDFU, 26 (52.0%) had also delayed seeking care. Prior consultation with a traditional healer (aOR 2.84, 95% CI 1.08-7.40), perceived causes as ingestion (water and food) (aOR 0.38 CI 0.16-0.89), and substance use (smoking and alcohol) (aOR 1.45 CI 0.98-2.14) were all associated with patient delay. Female gender was associated with LDFU (aOR 3.80, 95% CI 1.62-8.87) but not with delay. Other conditions as prior illness and heredity were also associated with LDFU but not delay (aOR 1.48 CI 1.01-2.17).

conclusionDelay and LDFU after referral from the pharmacies were substantial. Notable effects of diagnosis and female gender indicate a need for more attention to women's health to promote timely and sustained TB treatment. Public awareness to counter misconceptions about the causes of TB is needed.

Indexed as

AdolescentAdultAgedAmbulatory Care FacilitiesAwarenessDelayed DiagnosisDelivery of Health CareEpidemiologic MethodsFemaleHumansMaleMiddle AgedPatient Acceptance of Health CarePharmaciesReferral and ConsultationSex DistributionCultural epidemiologyGenderHelp-seeking behaviourLoss to follow-upPatient delayTuberculosis

Identifiers

PMID30953502
PMCPMC6451234
OpenAlexW2942879959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.