Evidence map›Paper›PMID 30953474›Full record

ArticleBMC pregnancy and childbirth2019

Risk of adverse pregnancy outcomes and seroprevalence for brucellosis in pregnant women exposed to goats or raw goat products in southern Thailand: a prospective cohort study.

Kan Kledmanee, Tippawan Liabsuetrakul, Somporn Sretrirutchai

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kan KledmaneeEpidemiology Unit, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Tippawan LiabsuetrakulEpidemiology Unit, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand. ltippawa@yahoo.com.ORCID http://orcid.org/0000-0001-7687-5629
Somporn SretrirutchaiDepartment of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Prince of Songkla University · TH

Funding

The Graduate School Dissertation Funding and an Excellence Center of the Epidemiology Unit Scholarship, Prince of Songkla University NoneThe National Science and Technology Development Agency NoneThe Royal Golden Jubilee Ph.D. Program Grant No. PHD/0098/2557
6 · The paper itself

Abstract

backgroundPregnant women infected with brucellosis have been shown to have higher odds of having been exposed to goats and raw goat products and adverse pregnancy outcomes. However, information on these associations in asymptomatic pregnant women is limited, particularly in the brucellosis-endemic areas. This study aimed to assess the association of a history of exposure to goats and/or raw goat products and the serological status of anti-Brucella abortus immunoglobulin G (IgG) with adverse pregnancy outcomes among pregnant women, and explore factors associated with having exposure to goats and/or raw goat products.

methodsA prospective cohort study was conducted among pregnant women from July 2015 to July 2016 at Songkhla province in southern Thailand. All pregnant women who came for antenatal care (ANC) visits were approached. Blood samples from the women who agreed to participate were randomly tested for anti-Brucella abortus IgG. The women were then followed for adverse pregnancy outcomes.

resultsOf 666 pregnant women, the majority (74.4%) were aged 20-34 years and Muslim (89.2%), 30.6% indicated exposure to goats or raw goat products, and 17.3% had adverse pregnancy outcomes. Women rearing goats at home or having neighbors rearing goats were more likely to be exposed to goats or raw goat products by cutaneous contact. Of 465 women having a blood test, 3.7% had seropositive results for anti-Brucella abortus IgG. No association with adverse pregnancy outcomes was found in the women reporting any exposure to goat and raw goat products. Having the first ANC visit at the first trimester and history of preterm birth or low birth weight newborn were independent risk factors of adverse pregnancy outcomes. Women who had positive serological results were more likely to have a history of drinking raw goat milk than those who had negative results significantly.

conclusionsAlthough no association between past exposure with goats and raw goat products and adverse pregnancy outcomes was found, women with past exposure showed positive anti-Brucella abortus IgG. Counseling on avoiding consumption of raw goat milk would be beneficial to prevent goat-related infection in pregnant women in this area.

Indexed as

Pregnancy OutcomeAdultAnimalsBrucellosisFemaleGoatsHumansMaternal ExposurePregnancyPregnancy Complications, InfectiousProspective StudiesRisk FactorsSeroepidemiologic StudiesThailandYoung AdultAdverse pregnancy outcomeBrucellosisExposureGoatPregnant womenRaw goat products

Identifiers

PMID30953474
PMCPMC6451268
OpenAlexW2944583673

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.