Evidence map›Paper›PMID 30953432›Full record

ArticleMicrobiology spectrum2019

The Interplay between

Annika Hausmann, Wolf-Dietrich Hardt

Abstract read
In one paragraph

Article in Microbiology spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Plant-Derived Phenolic Acids Limit the Pathogenesis ofMolecules (Basel, Switzerland) · 2024
    Article
  7. Review
  8. MafK acceleratesAging · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Anti-inflammatory Effect of ProbioticFrontiers in microbiology · 2021
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Annika HausmannInstitute of Microbiology, D-BIOL ETH Zurich, Zurich, Switzerland.
Wolf-Dietrich HardtInstitute of Microbiology, D-BIOL ETH Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infection results in a dynamic interplay between the pathogen and its host. The underlying interactions are multilayered, and the cellular responses are modulated by the local environment. The intestine is a particularly interesting tissue regarding host-pathogen interaction. It is densely colonized by commensal microbes and a portal of entry for ingested pathogens. This necessitates constant monitoring of microbial stimuli in order to maintain homeostasis during encounters with benign microbiota and to trigger immune defenses in response to bacterial pathogens. Homeostasis is maintained by physical barriers (the mucus layer and epithelium), chemical defenses (antimicrobial peptides), and innate immune responses (NLRC4 inflammasome), which keep the bacteria from reaching the sterile lamina propria. Intestinal pathogens represent potent experimental tools to probe these barriers and decipher how pathogens can circumvent them. The streptomycin mouse model of oral

Indexed as

AnimalsApoptosis Regulatory ProteinsBacterial ProteinsCalcium-Binding ProteinsCytokinesDisease Models, AnimalEnterocytesGene Expression Regulation, BacterialGenes, BacterialHomeostasisHost-Pathogen InteractionsImmunity, InnateInflammationIntestinal MucosaIntestinesMiceApoptosis Regulatory ProteinsBacterial ProteinsCalcium-Binding ProteinsCytokinesIpaf protein, mouseSpi1 protein, SalmonellaStreptomycinVirulence Factors

Identifiers

PMID30953432
PMCPMC11588296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.