Evidence map›Paper›PMID 30953212›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2019

Dynamic creep properties of a novel nanofiber hernia mesh in abdominal wall repair.

B East, M Plencner, M Otahal, E Amler, A C de Beaux

Abstract read
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In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

B East3rd Department of Surgery, Motol University Hospital, V uvalu 84, 15006, Prague, Czech Republic. Barbora.east@gmail.com.
M PlencnerDepartment of Biophysics, 2nd Medical Faculty, Charles University, V uvalu 84, 15006, Prague, Czech Republic.
M OtahalDepartment of Biomechanics and Anatomy, Faculty of Physical Education and Sport, Charles University, José Martího 31, 162 52, Prague, Czech Republic.
E AmlerDepartment of Biophysics, 2nd Medical Faculty, Charles University, V uvalu 84, 15006, Prague, Czech Republic.
A C de BeauxRoyal Infirmary of Edinburgh, Little France Crescent, Edinburgh, EH16 4SA, UK.
Charles University · CZEdinburgh Royal Infirmary · GBUniversity Hospital in Motol · CZ

Funding

Ministerstvo Zdravotnictví Ceské Republiky NV17-32285A
6 · The paper itself

Abstract

purposeIncisional hernia is the most common complication following abdominal surgery. While mesh repair is common, none of the current meshes mimic the physiology of the abdominal wall. This study compares suture only repair with polypropylene mesh and a prototype of a novel implant (poly-epsilon-caprolactone nanofibers) and their influence on the physiology of an abdominal wall in an animal model.

methods27 Chinchilla rabbits were divided into six groups based on the type of the implant. Midline abdominal incision was repaired using one of the compared materials with suture alone serving as the control. 6 weeks post-surgery animals were killed and their explanted abdominal wall subjected to biomechanical testing.

resultsBoth-hysteresis and maximum strength curves showed high elasticity and strength in groups where the novel implant was used. Polypropylene mesh proved as stiff and fragile compared to other groups.

conclusionPoly-epsilon-caprolactone nanofiber scaffold is able to improve the dynamic properties of healing fascia with no loss of maximum tensile strength when compared to polypropylene mesh in an animal model.

Indexed as

Hernia, AbdominalIncisional HerniaSurgical MeshAbdominoplastyAnimalsDisease Models, AnimalElasticityHerniorrhaphyMaterials TestingNanofibersPolypropylenesRabbitsTensile StrengthPolypropylenesDynamic propertiesHerniaNanofibresPCL

Identifiers

PMID30953212
OpenAlexW2929986547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.