Evidence map›Paper›PMID 30953190›Full record

ReviewArchives of gynecology and obstetrics2019

An update on the role of Atopobium vaginae in bacterial vaginosis: what to consider when choosing a treatment? A mini review.

Werner Mendling, Ana Palmeira-de-Oliveira, Stephan Biber, Valdas Prasauskas

Open access · hybridAbstract readReview
In one paragraph

Review in Archives of gynecology and obstetrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 76 citations in OpenAlex.

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  16. Microorganisms · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Werner MendlingGerman Center for Infections in Obstetrics and Gynaecology, Wuppertal, Germany. w.mendling@t-online.de.ORCID 0000-0002-6845-9411
Ana Palmeira-de-OliveiraLabfit-HPRD: Health Products Research and Development, Lda, Covilhã, Portugal.
Stephan BiberScientific and Medical Department, Medinova AG, Zurich, Switzerland.
Valdas PrasauskasScientific and Medical Department, Medinova AG, Zurich, Switzerland.
University of Beira Interior · PTWuppertal Institute for Climate, Environment and Energy · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBacterial vaginosis (BV) is the most common vaginal disorder in reproductive-age women. The condition is characterised by the replacement of a healthy, lactobacilli-dominated vaginal microbiota by anaerobic and facultative anaerobic bacteria. BV increases the risk of acquisition of STIs and is associated with pregnancy complications. Although the composition of the bacteria in BV varies between individuals, there are some species such as Gardnerella, Atopobium, Mycoplasma, Snethia, Megasphera, Dialister, etc., that are found most frequently. MATERIAL AND

methodsLiterature research to the importance of Atopobium vaginae in BV and treatment options.

resultsAtopobium (A.) vaginae is an important component of the complex abnormal vaginal flora in BV; even though A. vaginae, like Gardnerella vaginalis, has also been detected in the normal flora, it is much more common in BV patients. A. vaginae has been shown to play an important role in the pathophysiology of BV and is thought to be at least a partial cause of the known negative sequelae. The presence of A. vaginae in the BV-associated biofilms and its resistance to some antimicrobial substances has been described - this seems to have a major impact on treatment outcome.

conclusionCurrent scientific data demonstrate that dequalinium chloride (Fluomycin

Indexed as

ActinobacteriaAnti-Infective AgentsFemaleHumansVaginaVaginosis, BacterialAnti-Infective AgentsAtopobium vaginaeBacterial biofilmBacterial vaginosisClindamycinDequalinium chlorideMetronidazoleMicrobial resistance

Identifiers

PMID30953190
PMCPMC6560015
OpenAlexW2928051298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.