Evidence map›Paper›PMID 30953028›Full record

ReviewBone marrow transplantation2019

Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019.

Rafael F Duarte, Myriam Labopin, Peter Bader, Grzegorz W Basak, Chiara Bonini, Christian Chabannon, Selim Corbacioglu, Peter Dreger, Carlo Dufour, Andrew R Gennery and 12 more

2 registry-linked trialsOpen access · bronzeAbstract readHistorical ArticleReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 144 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 3 pooled it
31.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06845592 narecruitingnot on this mapstarted 2025, after this paper: background citation

SHARP - Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia

TypeinterventionalSponsorUniversity Of PerugiaRan2025 to 2031Enrolled51ConditionsAcute Myeloid Leukaemia (AML), Acute Lymphoblastic Leukemia ALL, High Risk Leukaemia, Leukaemia RelapseArmstotal marrow/lymphoid irradiation
NCT07481669 phase2recruitingnot on this mapstarted 2026, after this paper: background citation

Autologous Stem Cell Transplantation With TEAM (Thiotepa, Etoposide, Cytarabine, Melphalan) Conditioning for Lymphoma Patients With High Risk of Central Nervous System Relapse

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2026 to 2028Enrolled45ConditionsLymphoma Patients With High-risk of Central Nervous System RelapseArmsTEAM regimen (thiotepa, etoposide, cytarabine and melphalan)
3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 3 syntheses or guidelines pooled it, 323 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Prospective Study of a Novel, Radiation-Free, Reduced-Intensity Bone Marrow Transplantation Platform for Primary Immunodeficiency Diseases.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Trial
  7. Trial
  8. Article
  9. Impact of CD34British journal of haematology · 2026
    Article
  10. Article
  11. Article
  12. Allogeneic Hematopoietic Cell Transplantation for Relapsed/Refractory Hodgkin Lymphoma: A Multicenter Real-World ExperienceTurkish journal of haematology : official journal of Turkish Society of Haematology · 2026
    Article
  13. Observational
  14. Patients' symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation-patients' own expressions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 14 institutions in 8 countries.

Rafael F DuarteHospital Universitario Puerta de Hierro Majadahonda - Universidad Autónoma de Madrid, Madrid, Spain. rduarte.work@gmail.com.
Myriam LabopinEBMT Paris Study Office, Hopital Saint Antoine, Paris, France.
Peter BaderGoethe University Hospital, Frankfurt/Main, Germany.
Grzegorz W BasakMedical University of Warsaw, Warsaw, Poland.
Chiara BoniniVita-Salute San Raffaele University & Ospedale San Raffaele Scientific Institute, Milan, Italy.
Christian ChabannonInstitut Paoli Calmettes & Centre d'Investigations Cliniques en Biothérapies, Marseille, France.ORCID http://orcid.org/0000-0002-3755-4889
Selim CorbaciogluUniversity of Regensburg, Regensburg, Germany.
Peter DregerMedizinische Klinik V, Universität Heidelberg, Heidelberg, Germany.
Carlo DufourGiannina Gaslini Children's Hospital, Genoa, Italy.
Andrew R GenneryGreat North Children's Hospital, Newcastle-Upon-Tyne, UK.
Jürgen KuballUniversity Medical Center Utrecht, Utrecht, The Netherlands.
Arjan C LankesterWillem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.
Francesco LanzaRomagna Transplant Network, Ravenna, Italy.
Silvia MontotoBarts Health NHS Trust, London, UK.
Arnon NaglerChaim Sheva Medical Center, Tel-Hashomer, Israel.
Régis Peffault de LatourSaint-Louis Hospital, Paris Diderot University, Paris, France.
John A SnowdenSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Jan StyczynskiCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Ibrahim Yakoub-AghaCHU de Lille, LIRIC, INSERM U995, Université de Lille, 59000, Lille, France.
Nicolaus KrögerUniversity Hospital Eppendorf, Hamburg, Germany.
Mohamad MohtyHopital Saint Antoine, Sorbonne Université, Paris, France.
European Society for Blood and Marrow Transplantation (EBMT)
Barts Health NHS Trust · GBDélégation Paris 7 · FRGoethe University Frankfurt · DEHeidelberg University · DEInserm · FRLeiden University Medical Center · NLSorbonne Université · FRVita-Salute San Raffaele University · ITInstitut Paoli-Calmettes · FRIstituto Giannina Gaslini · ITNicolaus Copernicus University · PLUniversidad Autónoma de Madrid · ESUniversität Hamburg · DEUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the seventh special EBMT report on the indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders. Our aim is to provide general guidance on transplant indications according to prevailing clinical practice in EBMT countries and centres. In order to inform patient decisions, these recommendations must be considered together with the risk of the disease, the risk of the transplant procedure and the results of non-transplant strategies. In over two decades since the first report, the EBMT indications manuscripts have incorporated changes in transplant practice coming from scientific and technical developments in the field. In this same period, the establishment of JACIE accreditation has promoted high quality and led to improved outcomes of patient and donor care and laboratory performance in transplantation and cellular therapy. An updated report with operating definitions, revised indications and an additional set of data with overall survival at 1 year and non-relapse mortality at day 100 after transplant in the commonest standard-of-care indications is presented. Additional efforts are currently underway to enable EBMT member centres to benchmark their risk-adapted outcomes as part of the Registry upgrade Project 2020 against national and/or international outcome data.

Indexed as

EuropeHematologic DiseasesHematopoietic Stem Cell TransplantationHistory, 21st CenturyHumansImmune System DiseasesNeoplasmsTransplantation Conditioning

Identifiers

PMID30953028
OpenAlexW2935210822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.