Evidence map›Paper›PMID 30953026›Full record

ArticleBone marrow transplantation2019

Fertility preservation from the point of view of hematopoietic cell transplant specialists-a worldwide-web-based survey analysis.

Heli Alexandroni, Gon Shoham, Rachel Levy-Toledano, Arnon Nagler, Mohamad Mohty, Rafael Duarte, Milton Leong, Zeev Shoham

Abstract read
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In one paragraph

Article in Bone marrow transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Heli Alexandroni *The Reproductive Medicine and IVF Unit, Kaplan Medical Center, 76100, Rehovot, Israel.
Gon Shoham *Sackler Faculty of Medicine, Tel Aviv University, P.O.B. 39040, Ramat Aviv, 69978, Tel Aviv, Israel.
Rachel Levy-ToledanoTeva Europe, Amsterdam, The Netherlands.
Arnon NaglerDivision of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Mohamad MohtyDepartment of Haematology, Saint Antoine Hospital, INSERM UMRS 938, University Pierre and Marie Curie, Paris, France.
Rafael DuarteHospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Milton LeongIVF Clinic, The Women's Clinic, 12/F, Central Tower, 28 Queen's Road Central, Central, Hong Kong, China.
Zeev ShohamThe Reproductive Medicine and IVF Unit, Kaplan Medical Center, Pasternak Street, 76100, Rehovot, Israel. zeev1@mail.huji.ac.il.
Kaplan Medical Center · ILHospital Universitario Puerta de Hierro Majadahonda · ESInserm · FRLondon Women's Clinic · GBSheba Medical Center · ILTel Aviv University · ILTeva Pharmaceuticals (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increase in cancer survival, men and women have a chance to conceive children post-recovery. This study aims to better understand hematopoietic cell transplant (HCT) specialist practices and opinions related to fertility preservation for hematological malignancy patients. Survey requests were emailed to 586 European Society for Blood and Marrow Transplantation (EBMT) members. Respondents completed the mostly multiple-choice questionnaire on the IVF-Worldwide.com website. Results were reported as a percentage of respondents. Responses were submitted by 150 HCT specialists from 41 (of 195) countries worldwide. The survey showed that most HCT specialists (87%) are aware of and inform patients that chemotherapy, radiotherapy, and transplantation could harm fertility. Specialists referred 56% of their male patients to fertility preservation but only 36% of their female patients; many pre-pubertal or near post-menopausal patients were not referred. This indicates that barriers may be preventing specialists from referring patients for fertility preservation. Many HCT specialists do not know about or use international fertility preservation recommendations, indicating that new protocols for enhancing awareness are needed. Establishing a referral process protocol to reproductive specialists should be considered. When non-urgent treatment can be deferred for 10-20 days, patients can have a sufficient window to undergo certain fertility preservation procedures.

Indexed as

Fertility PreservationHematopoietic Stem Cell TransplantationAdolescentAdultChildFemaleHumansInfertilityMaleSurveys and Questionnaires

Identifiers

PMID30953026
OpenAlexW2930835506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.