Evidence map›Paper›PMID 30952973›Full record

ArticleModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc2019

Methotrexate-associated lymphoproliferative disorders of T-cell phenotype: clinicopathological analysis of 28 cases.

Akira Satou, Tetsuya Tabata, Hiroaki Miyoshi, Kei Kohno, Yuka Suzuki, Daisuke Yamashita, Kazuyuki Shimada, Tomonori Kawasaki, Yasuharu Sato, Tadashi Yoshino and 4 more

Abstract read
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In one paragraph

Article in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  7. Review
  8. Analysis of Notch1 protein expression in methotrexate-associated lymphoproliferative disorders.Journal of clinical and experimental hematopathology : JCEH · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Akira SatouDepartment of Surgical Pathology, Aichi Medical University Hospital, Nagakute, Japan. satoakira@aichi-med-u.ac.jp.
Tetsuya TabataDepartment of Pathology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.
Hiroaki MiyoshiDepartment of Pathology, School of Medicine, Kurume University, Kurume, Japan.ORCID http://orcid.org/0000-0002-2356-3725
Kei KohnoDepartment of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Yuka SuzukiDepartment of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Daisuke YamashitaDepartment of Pathology, Kobe City Hospital Organization, Kobe City Medical Center General Hospital, Kobe, Japan.
Kazuyuki ShimadaDepartment of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tomonori KawasakiDepartment of Pathology, Saitama Medical University International Medical Center, Saitama, Japan.
Yasuharu SatoDivision of Pathophysiology, Okayama University Graduate School of Health Sciences, Okayama, Japan.
Tadashi YoshinoDepartment of Pathology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.
Koichi OhshimaDepartment of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Taishi TakaharaDepartment of Surgical Pathology, Aichi Medical University Hospital, Nagakute, Japan.
Toyonori TsuzukiDepartment of Surgical Pathology, Aichi Medical University Hospital, Nagakute, Japan.ORCID http://orcid.org/0000-0002-4855-4366
Shigeo NakamuraDepartment of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methotrexate-associated lymphoproliferative disorders are categorized as "other immunodeficiency-associated lymphoproliferative disorders in the WHO classification. Methotrexate-associated lymphoproliferative disorder is mainly a B-cell lymphoproliferative disorders or Hodgkin lymphoma type, whereas T-cell lymphoproliferative disorders are relatively rare (4-8%). Only a small number of methotrexate-associated T-cell lymphoproliferative disorders have been detailed thus far. Because of the rarity, methotrexate-associated T-cell lymphoproliferative disorder has not been well studied and its clinicopathological characteristics are unknown. A total of 28 cases of methotrexate-associated T-cell lymphoproliferative disorders were retrospectively analyzed. Histologically and immunohistochemically, they were divided into three main types: angioimmunoblastic T-cell lymphoma (n = 19), peripheral T-cell lymphoma, NOS (n = 6), and CD8

Indexed as

AgedAged, 80 and overCell ProliferationFemaleHerpesvirus 4, HumanHumansImmunoblastic LymphadenopathyImmunosuppressive AgentsLymphoma, T-Cell, PeripheralLymphoproliferative DisordersMaleMethotrexateMiddle AgedPhenotypePrognosisRetrospective StudiesImmunosuppressive AgentsMethotrexate

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.