ArticleScientific reports2019
Evolution of folate biosynthesis and metabolism across algae and land plant lineages.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 80 citations in OpenAlex.
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- Atlas of one-carbon metabolism in conventional and germ-free mice reveals folate as a key determinant of biochemical pathways.Nature metabolism · 2026Article
- From genome to drug targets: computational subtractive genomics reveals novel anti-filarial targets in Wuchereria bancrofti and identifies plant-based inhibitors of β-1,4-mannosyltransferase, a high-priority target.Molecular diversity · 2026Article
- Foliar folic acid application enhances nitrogen assimilation and improves quality-related metabolites accumulation inFrontiers in plant science · 2026Article
- TheISME communications · 2026Article
- Comparative Proteomic Analysis of Self-CompatiblePlant direct · 2025Article
- Plasma membrane folate transport in fungi and plants is mediated by members of the oligopeptide transporter (OPT) family.The Biochemical journal · 2025Article
- An Allele of Glutamate Formiminotransferase Triggers 5-Methyl-Tetrahydrofolate-to-MeFox Conversion and Facilitates Folate Biofortification in Maize.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Whole genome sequence of an edible mushroom Strobilomyces alpinus (Boletaceae).G3 (Bethesda, Md.) · 2025Article
- Identification and characterization of archaeal pseudomurein biosynthesis genes through pangenomics.mSystems · 2025Article
- Biological, dietetic and pharmacological properties of vitamin BNPJ science of food · 2025Review
- Folate depletion impact on the cell cycle results in restricted primary root growth in Arabidopsis.Plant molecular biology · 2025Article
- Phytochemicals, Organic Acid, and Vitamins in Red Rhapsody Strawberry-Content and Storage Stability.Foods (Basel, Switzerland) · 2025Article
- A de novo Gene Promotes Seed Germination Under Drought Stress in Arabidopsis.Molecular biology and evolution · 2025Article
- Transcriptomic Analysis Reveals the Effect of Urea on Metabolism ofLife (Basel, Switzerland) · 2024Article
- Dynamic evolution of the mTHF gene family associated with primary metabolism across life.BMC genomics · 2024Article
- Molecular Targets of Herbicides and Fungicides─Are There Useful Overlaps for Fungicide Discovery?Journal of agricultural and food chemistry · 2023Review
- Reduced γ-glutamyl hydrolase activity likely contributes to high folate levels in Periyakulam-1 tomato.Horticulture research · 2023Article
- Effect of Amino Acids on Folates Accumulation in Wheat Seedlings during Germination under Red Light Radiation.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tetrahydrofolate and its derivatives, commonly known as folates, are essential for almost all living organisms. Besides acting as one-carbon donors and acceptors in reactions producing various important biomolecules such as nucleic and amino acids, as well as pantothenate, they also supply one-carbon units for methylation reactions. Plants along with bacteria, yeast and fungi synthesize folates de novo and therefore constitute a very important dietary source of folates for animals. All the major steps of folate biosynthesis and metabolism have been identified but only few have been genetically characterized in a handful of model plant species. The possible differences in the folate pathway between various plant and algal species have never been explored. In this study we present a comprehensive comparative study of folate biosynthesis and metabolism of all major land plant lineages as well as green and red algae. The study identifies new features of plant folate metabolism that might open new directions to folate research in plants.
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