Evidence map›Paper›PMID 30952879›Full record

ArticleScientific reports2019

Inevitable isolation and the change of stress markers in hemodialysis patients during the 2015 MERS-CoV outbreak in Korea.

Yang Gyun Kim, Haena Moon, Se-Yun Kim, Yu-Ho Lee, Da-Wun Jeong, Kipyo Kim, Ju Young Moon, Young-Ki Lee, Ajin Cho, Hong-Seock Lee and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Development of the Adult Pandemic Attitude Scale (A-PAS).International journal of environmental research and public health · 2021
    Article
  7. Article
  8. International journal of environmental research and public health · 2021
    Article
  9. Article
  10. Psychometric Properties of the Greek Version of FCV-19S.International journal of mental health and addiction · 2021
    Article
  11. Sociodemographic Characteristics and Stress of People from Spain Confined by COVID-19.European journal of investigation in health, psychology and education · 2020
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Yang Gyun KimDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.
Haena MoonDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.
Se-Yun KimDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.
Yu-Ho LeeDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.
Da-Wun JeongDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.
Kipyo KimDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0003-4166-1801
Ju Young MoonDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea.
Young-Ki LeeHallym University College of Medicine, Internal Medicine, Seoul, Korea.
Ajin ChoHallym University College of Medicine, Internal Medicine, Seoul, Korea.
Hong-Seock LeeHallym University College of Medicine, Psychiatry, Seoul, Korea.
Hayne Cho ParkDepartment of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.
Sang-Ho LeeDivision of Nephrology, Kyung Hee University College of Medicine, Seoul, Korea. lshkidney@khu.ac.kr.
Kyung Hee University · KRHallym University · KRArmed Forces Capital Hospital · KRKyung Hee Cyber University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the outbreak of Middle East respiratory syndrome coronavirus(MERS-CoV) in 2015, one hemodialysis patient was infected with MERS-CoV, and the remaining hemodialysis(HD) patients (n = 83) and medical staff (n = 12) had to undergo dialysis treatment in an isolated environment. This study was performed to investigate the effects of stress caused by dialysis treatment under isolation. Plasma samples from the HD patients and medical staff were collected at the time of isolation(M0), the following month(M1), and three months after isolation(M3). Parameters for stress included circulating cell-free genomic DNA(ccf-gDNA), circulating cell-free mitochondria DNA(ccf-mtDNA), and pentraxin-3(PTX-3). Decreased values of Hct, kt/v and ca x p were recovered after the end of two weeks of isolation. The levels of ccf-gDNA and ccf-mtDNA were the highest at M0 and decreased gradually in both HD patients and the medical staff. The normalization of ccf-gDNA and ccf-mtDNA was significantly delayed in HD patients compared with the response in the medical staff. PTX-3 increased only in HD patients and was highest at M0, and it then gradually decreased. Medical isolation and subnormal quality of care during the MERS outbreak caused extreme stress in HD patients. Plasma cell-free DNA and PTX-3 seems to be good indicators of stress and quality of care in HD patients.

Indexed as

AdultBiomarkersCell-Free Nucleic AcidsCoronavirus InfectionsCross InfectionDisease OutbreaksDNA, MitochondrialFemaleHumansMaleMiddle AgedMiddle East Respiratory Syndrome CoronavirusRenal DialysisRepublic of KoreaBiomarkersCell-Free Nucleic AcidsDNA, Mitochondrial

Identifiers

PMID30952879
PMCPMC6450937
OpenAlexW2926970129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.