Evidence map›Paper›PMID 30952666›Full record

ArticleDevelopment (Cambridge, England)2019

A Cut/cohesin axis alters the chromatin landscape to facilitate neuroblast death.

Richa Arya, Seda Gyonjyan, Katherine Harding, Tatevik Sarkissian, Ying Li, Lei Zhou, Kristin White

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Genetics · 2019
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Richa AryaCutaneous Biology Research Center, Massachusetts General Hospital Research Institute/Harvard Medical School, Boston, MA 02129, USA.ORCID 0000-0003-4464-699X
Seda GyonjyanCutaneous Biology Research Center, Massachusetts General Hospital Research Institute/Harvard Medical School, Boston, MA 02129, USA.
Katherine HardingCutaneous Biology Research Center, Massachusetts General Hospital Research Institute/Harvard Medical School, Boston, MA 02129, USA.
Tatevik SarkissianCutaneous Biology Research Center, Massachusetts General Hospital Research Institute/Harvard Medical School, Boston, MA 02129, USA.
Ying LiDepartment of Molecular Genetics and Microbiology, College of Medicine/UF Health Cancer Center/UF Genetics Institute, University of Florida, Gainesville, FL 32610, USA.
Lei ZhouDepartment of Molecular Genetics and Microbiology, College of Medicine/UF Health Cancer Center/UF Genetics Institute, University of Florida, Gainesville, FL 32610, USA.
Kristin WhiteCutaneous Biology Research Center, Massachusetts General Hospital Research Institute/Harvard Medical School, Boston, MA 02129, USA Kristin.white@MGH.Harvard.edu.ORCID 0000-0003-0149-974X
Harvard University · USMacau University of Science and Technology · MOUniversity of Delhi · INUniversity of Florida Health · US

Funding

The regulation of cell death in vivoR01GM110477 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN, ZHOU, LEI · 2015 to 2018
$1.4M
Rapid Induction of apoptosis against viral infectionR01GM106174 · NIGMS · UNIVERSITY OF FLORIDA · PI ZHOU, LEI · 2014 to 2017
$1.1M
Nikon A1 laser scanning confocal microscope equipped for live imaging of cells anS10RR027673 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN · 2010 to 2010
$500k
Life and death decisions in Drosophila neural stem cellsR03NS092063 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN · 2015 to 2016
$174k
NCRR NIH HHS S10 RR027673NIGMS NIH HHS R01 GM106174NIGMS NIH HHS R01 GM110477NINDS NIH HHS R03 NS092063
6 · The paper itself

Abstract

Precise control of cell death in the nervous system is essential for development. Spatial and temporal factors activate the death of

Indexed as

AnimalsApoptosisCell Cycle ProteinsChromatinChromosomal Proteins, Non-HistoneCohesinsDrosophilaDrosophila ProteinsHomeodomain ProteinsNuclear ProteinsTranscription FactorsCell Cycle ProteinsChromatinChromosomal Proteins, Non-HistoneCohesinsct protein, DrosophilaDrosophila ProteinsHomeodomain ProteinsNuclear ProteinsTranscription FactorsCohesinCutDevelopmental cell deathDrosophilaNeuroblast

Identifiers

PMID30952666
PMCPMC6526717
OpenAlexW2952640048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.