Evidence map›Paper›PMID 30952665›Full record

ArticleDevelopment (Cambridge, England)2019

Cyclin B2 is required for progression through meiosis in mouse oocytes.

Enrico Maria Daldello, Xuan G Luong, Cai-Rong Yang, Jonathan Kuhn, Marco Conti

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
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  12. Article
  13. Meiotic Cell Cycle Progression in Mouse Oocytes: Role of Cyclins.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Regulation of oocyte maturation: Role of conserved ERK signaling.Molecular reproduction and development · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Enrico Maria DaldelloCenter for Reproductive Sciences, University of California, San Francisco, CA 94143, USA.
Xuan G LuongCenter for Reproductive Sciences, University of California, San Francisco, CA 94143, USA.
Cai-Rong YangCenter for Reproductive Sciences, University of California, San Francisco, CA 94143, USA.
Jonathan KuhnCell and Tissue Biology Department, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-2355-8982
Marco ContiCenter for Reproductive Sciences, University of California, San Francisco, CA 94143, USA contim@obgyn.ucsf.edu.ORCID 0000-0003-4755-9146
University of California, San Francisco · US

Funding

REPRODUCTIVE ENDOCRINOLOGYT32HD007263 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MELLON, SYNTHIA H · 1985 to 2023
$4.1M
RNA binding protein networks and translational control in mammalian oocytesR01GM116926 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONTI, MARCO · 2016 to 2023
$2.8M
The translational program in oocyte and early embryo developmentR01GM097165 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONTI, MARCO · 2011 to 2014
$1.4M
Wee Kinases and the Control of the Meiotic Cell CycleR01GM115241 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONTI, MARCO · 2015 to 2018
$1.2M
NICHD NIH HHS T32 HD007263NIGMS NIH HHS R01 GM097165NIGMS NIH HHS R01 GM115241NIGMS NIH HHS R01 GM116926
6 · The paper itself

Abstract

Cyclins associate with cyclin-dependent serine/threonine kinase 1 (CDK1) to generate the M phase-promoting factor (MPF) activity essential for progression through mitosis and meiosis. Although cyclin B1 (CCNB1) is required for embryo development, previous studies concluded that CCNB2 is dispensable for cell cycle progression. Given previous findings of high

Indexed as

AnimalsCyclin B1Cyclin B2FemaleMaleMeiosisMesothelinMiceMice, Mutant StrainsOocytesProto-Oncogene Proteins c-mosRNA, MessengerCcnb1 protein, mouseCcnb2 protein, mouseCyclin B1Cyclin B2MesothelinMsln protein, mouseProto-Oncogene Proteins c-mosRNA, MessengerCyclinsFertilityMeiosisMouse oocytesMPF

Identifiers

PMID30952665
PMCPMC6503990
OpenAlexW2896159420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.