ReviewNeuroscience and biobehavioral reviews2019
Validation of hippocampal biomarkers of cumulative affective experience.
Review in Neuroscience and biobehavioral reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Rodent tests of depression and anxiety: Construct validity and translational relevance.Cognitive, affective & behavioral neuroscience · 2024Review
- What is the role of the hippocampus and parahippocampal gyrus in the persistence of tinnitus?Human brain mapping · 2024Review
- Vulnerability of the Hippocampus to Insults: Links to Blood-Brain Barrier Dysfunction.International journal of molecular sciences · 2024Review
- Waking inactivity as a welfare indicator in laboratory mice: investigating postures, facial expressions and depression-like states.Royal Society open science · 2022Article
- Using non-invasive neuroimaging to enhance the care, well-being and experimental outcomes of laboratory non-human primates (monkeys).NeuroImage · 2021Review
- Beyond MRI: on the scientific value of combining non-human primate neuroimaging with metadata.NeuroImage · 2021Article
- Keel bone fractures induce a depressive-like state in laying hens.Scientific reports · 2020Article
- The 3Rs and Humane Experimental Technique: Implementing Change.Animals : an open access journal from MDPI · 2019Article
- Unpredictable Chronic Mild Stress Suppresses the Incorporation of New Neurons at the Caudal Pole of the Chicken Hippocampal Formation.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Progress in improving the welfare of captive animals has been hindered by a lack of objective indicators to assess the quality of lifetime experience, often called cumulative affective experience. Recent developments in stress biology and psychiatry have shed new light on the role of the mammalian hippocampus in affective processes. Here we review these findings and argue that structural hippocampal biomarkers demonstrate criterion, construct and content validity as indicators of cumulative affective experience in mammals. We also briefly review emerging findings in birds and fish, which have promising implications for applying the hippocampal approach to these taxa, but require further validation. We hope that this review will motivate welfare researchers and neuroscientists to explore the potential of hippocampal biomarkers of cumulative affective experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.