Evidence map›Paper›PMID 30951372›Full record

Trial reportAmerican journal of respiratory and critical care medicine2019

The Effect of Aclidinium on Symptoms Including Cough in Chronic Obstructive Pulmonary Disease: A Phase 4, Double-Blind, Placebo-controlled, Parallel-Group Study.

Jaclyn A Smith, Lorcan McGarvey, Alyn H Morice, Surinder S Birring, Jadwiga A Wedzicha, Massimo Notari, Antonio Zapata, Rosa Segarra, Beatriz Seoane, Diana Jarreta

Open access · hybridAbstract readClinical Trial, Phase IVLetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 4 countries.

Jaclyn A SmithManchester University NHS Foundation TrustManchester, United Kingdom.ORCID 0000-0001-8837-4928
Lorcan McGarveyQueen's University BelfastBelfast, United Kingdom.
Alyn H MoriceCastle Hill HospitalCottingham, United Kingdom.
Surinder S BirringKing's College LondonLondon, United Kingdom.
Jadwiga A WedzichaImperial College LondonLondon, United Kingdom.
Massimo NotariA. Menarini Farmaceutica Internazionale s.r.l.Florence, Italy.
Antonio ZapataLaboratorios MenariniS.A. Badalona, Spain.
Rosa SegarraR&D Centre, AstraZeneca PLCBarcelona, Spainand.
Beatriz SeoaneR&D Centre, AstraZeneca PLCBarcelona, Spainand.
Diana JarretaR&D Centre, AstraZeneca PLCBarcelona, Spainand.
AstraZeneca (Brazil) · BRBadalona Serveis Assistencials · ESImperial College London · GBKing's College London · GBMenarini Group (Italy) · ITQueen's University Belfast · GBUniversity of Hull · GBUniversity of Manchester · GB

Funding

Department of Health RP-PG-0109-10056Medical Research Council G0800570Medical Research Council G1001365Medical Research Council G1001372Wellcome Trust 207504/B/17/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overBronchodilator AgentsCoughDouble-Blind MethodFemaleHumansMaleMiddle AgedMuscarinic AntagonistsPlacebosPulmonary Disease, Chronic ObstructiveTropanesaclidinium bromideBronchodilator AgentsMuscarinic AntagonistsPlacebosTropanes

Identifiers

PMID30951372
PMCPMC6727161
OpenAlexW2970181192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.