Evidence map›Paper›PMID 30950607›Full record

ArticleBiochemistry2019

Characterizing Watson-Crick versus Hoogsteen Base Pairing in a DNA-Protein Complex Using Nuclear Magnetic Resonance and Site-Specifically

Huiqing Zhou, Bharathwaj Sathyamoorthy, Allison Stelling, Yu Xu, Yi Xue, Ying Zhang Pigli, David A Case, Phoebe A Rice, Hashim M Al-Hashimi

Abstract read
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Nature communications · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. ACS physical chemistry Au · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Infrared Spectroscopic Observation of a G-CAngewandte Chemie (International ed. in English) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huiqing ZhouDepartment of Biochemistry , Duke University School of Medicine , Durham , North Carolina 27710 , United States.ORCID 0000-0002-9220-4742
Bharathwaj SathyamoorthyDepartment of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhopal 462066 , India.
Allison StellingDepartment of Biochemistry , Duke University School of Medicine , Durham , North Carolina 27710 , United States.
Yu XuDepartment of Chemistry , Duke University , Durham , North Carolina 27708 , United States.
Yi XueTsinghua-Peking Center for Life Sciences, School of Life Sciences , Tsinghua University , Beijing 100084 , China.
Ying Zhang PigliBiochemistry and Molecular Biology , The University of Chicago , Chicago , Illinois 60637 , United States.
David A CaseDepartment of Chemistry and Chemical Biology , Rutgers University , Piscataway , New Jersey 08854 , United States.ORCID 0000-0003-2314-2346
Phoebe A RiceBiochemistry and Molecular Biology , The University of Chicago , Chicago , Illinois 60637 , United States.
Hashim M Al-HashimiDepartment of Biochemistry , Duke University School of Medicine , Durham , North Carolina 27710 , United States.

Funding

The Center for HIV RNA Studies (CRNA)P50GM103297 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAYIE, KWAKU · 2012 to 2016
$21.7M
Role of DNA structural dynamics in mutagenesis and oncogenesisR01GM089846 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Hashim M Al-Hashimi · 2010 to 2026
$5.2M
NIGMS NIH HHS P50 GM103297NIGMS NIH HHS R01 GM089846
6 · The paper itself

Abstract

A( syn)-T and G( syn)-C

Indexed as

Base PairingNucleic Acid ConformationBase SequenceCarbon IsotopesCrystallography, X-RayDNADNA-Binding ProteinsMacromolecular SubstancesMagnetic Resonance SpectroscopyModels, MolecularMolecular StructureNitrogen IsotopesNucleotidesProtein DomainsCarbon IsotopesDNADNA-Binding ProteinsMacromolecular SubstancesNitrogen IsotopesNucleotides

Identifiers

PMID30950607
PMCPMC8091065

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.