Evidence map›Paper›PMID 30950601›Full record

ArticleBiochemistry2019

RNA Polymerase: Step-by-Step Kinetics and Mechanism of Transcription Initiation.

Kate L Henderson, Claire E Evensen, Cristen M Molzahn, Lindsey C Felth, Sarah Dyke, Guanyu Liao, Irina A Shkel, M Thomas Record

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kate L HendersonDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.ORCID 0000-0003-3051-6692
Claire E EvensenDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Cristen M MolzahnDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Lindsey C FelthDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Sarah DykeDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Guanyu LiaoDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Irina A ShkelDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
M Thomas RecordDepartment of Biochemistry , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
University of Wisconsin–Madison · US

Funding

Mechanisms of RNA Polymerase-Promoter and lac Repressor-Operator InteractionsR35GM118100 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI RECORD, M. THOMAS · 2016 to 2020
$2.6M
Promoter and RNA Polymerase Determinants in Transcription InitiationF32GM122303 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HENDERSON, KATE LYNNE · 2017 to 2018
$116k
NIGMS NIH HHS F32 GM122303NIGMS NIH HHS R35 GM118100
6 · The paper itself

Abstract

To determine the step-by-step kinetics and mechanism of transcription initiation and escape by E. coli RNA polymerase from the λP

Indexed as

Transcription Initiation, GeneticAlgorithmsDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsKineticsModels, GeneticNucleotidesOligoribonucleotidesPromoter Regions, GeneticRNA, BacterialUridine Triphosphateadenosine triphosphate uridine monophosphateDNA-Directed RNA PolymerasesEscherichia coli ProteinsNucleotidesOligoribonucleotidesRNA, BacterialUridine Triphosphate

Identifiers

PMID30950601
PMCPMC6504642
OpenAlexW2928370004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.