Evidence map›Paper›PMID 30950529›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2019

Alexandra Svyatova, Ivan V Skovpin, Nikita V Chukanov, Kirill V Kovtunov, Eduard Y Chekmenev, Andrey N Pravdivtsev, Jan-Bernd Hövener, Igor V Koptyug

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. High HThe journal of physical chemistry letters · 2025
    Article
  4. Molecules, Up Your Spins!Molecules (Basel, Switzerland) · 2024
    Article
  5. Scientific reports · 2024
    Article
  6. Article
  7. LIGHT-SABRE Hyperpolarizes 1-The journal of physical chemistry. C, Nanomaterials and interfaces · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Synthetic Approaches forChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  17. Synthesis andChemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
  18. Parahydrogen-Induced Hyperpolarization of Gases.Angewandte Chemie (International ed. in English) · 2020
    Review
  19. Article
  20. Remarkable Levels ofThe journal of physical chemistry. B · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra SvyatovaInternational Tomography Center, SB RAS, 3A Institutskaya st., Novosibirsk, 630090, Russia.
Ivan V SkovpinInternational Tomography Center, SB RAS, 3A Institutskaya st., Novosibirsk, 630090, Russia.
Nikita V ChukanovInternational Tomography Center, SB RAS, 3A Institutskaya st., Novosibirsk, 630090, Russia.
Kirill V KovtunovInternational Tomography Center, SB RAS, 3A Institutskaya st., Novosibirsk, 630090, Russia.ORCID http://orcid.org/0000-0001-7577-9619
Eduard Y ChekmenevDepartment of Chemistry, Wayne State University, Karmanos Cancer Institute (KCI), Integrative Biosciences (Ibio), Detroit, MI 48202, USA.
Andrey N PravdivtsevSection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology University Medical Center Schleswig-Holstein (UKSH), Kiel University, Am Botanischen Garten 14, 24118, Kiel, Germany.
Jan-Bernd HövenerSection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology University Medical Center Schleswig-Holstein (UKSH), Kiel University, Am Botanischen Garten 14, 24118, Kiel, Germany.
Igor V KoptyugInternational Tomography Center, SB RAS, 3A Institutskaya st., Novosibirsk, 630090, Russia.

Funding

Pure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB020323 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2015 to 2016
$416k
Magnetic Resonance Spectroscopy and Molecular Imaging of Metabolic Pathways in CancerR21CA220137 · NCI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2017 to 2019
$390k
DFG in the Emmy Noether Program HO 4604/2-1National Science Foundation CHE-1836308NCI NIH HHS R21 CA220137NIBIB NIH HHS R21 EB020323NIH HHS 1R21EB020323 and R21CA220137Research Training Circle Materials for Brain GRK 2154Russian Foundation for Basic Research 19-53-12013Russian Science Foundation 17-73-20030Zukunftsprogramm Wirtschaft of Schleswig-Holstein 122-09-053
6 · The paper itself

Abstract

Magnetic Resonance Imaging (MRI) is a powerful non-invasive diagnostic method extensively used in biomedical studies. A significant limitation of MRI is its relatively low signal-to-noise ratio, which can be increased by hyperpolarizing nuclear spins. One promising method is Signal Amplification By Reversible Exchange (SABRE), which employs parahydrogen as a source of hyperpolarization. Recent studies demonstrated the feasibility to improve MRI sensitivity with this hyperpolarization technique. Hyperpolarized

Indexed as

CatalysisCoordination ComplexesIsotope LabelingMagnetic Resonance ImagingNiacinamideNitrogen IsotopesPyridinesCoordination ComplexesNiacinamideNitrogen-15Nitrogen IsotopespyridinePyridines15N MRIhyperpolarizationmolecular imagingparahydrogenSABRE

Identifiers

PMID30950529
PMCPMC6679352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.