ArticleEvolution; international journal of organic evolution2019
Antagonistic selection and pleiotropy constrain the evolution of plant chemical defenses.
Article in Evolution; international journal of organic evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Pleiotropy and the evolutionary stability of plastic phenotypes: a geometric framework.G3 (Bethesda, Md.) · 2026Article
- Causes of delayed angiosperm diversification: The photosynthetic revolution, increased opportunity costs of anti-herbivore defenses, selection for qualitative toxins, and acceleration of plant-herbivore coevolution.American journal of botany · 2025Review
- Infection Patterns ofPlants (Basel, Switzerland) · 2025Article
- Uncoupling FRUITFULL's functions through modification of a protein motif identified by co-ortholog analysis.Nucleic acids research · 2024Article
- Depicting the phenotypic space of the annual plantEcology and evolution · 2021Article
- Herbivore-induced defenses are not under phylogenetic constraints in the genusEcology and evolution · 2021Article
- The ecological, genetic and genomic architecture of local adaptation and population differentiation inProceedings. Biological sciences · 2021Article
- Herbivore-Mediated Selection on Floral Display Covaries Nonlinearly With Plant-Antagonistic Interaction Intensity Among Primrose Populations.Frontiers in plant science · 2021Article
- Comparative Metabolomics of Fruits and Leaves in a Hyperdiverse Lineage Suggests Fruits Are a Key Incubator of Phytochemical Diversification.Frontiers in plant science · 2021Article
- Evolutionary Genomics of Plant Gametophytic Selection.Plant communications · 2020Review
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2 authors.
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Abstract
When pleiotropy is present, genetic correlations may constrain the evolution of ecologically important traits. We used a quantitative genetics approach to investigate constraints on the evolution of secondary metabolites in a wild mustard, Boechera stricta. Much of the genetic variation in chemical composition of glucosinolates in B. stricta is controlled by a single locus, BCMA1/3. In a large-scale common garden experiment under natural conditions, we quantified fitness and glucosinolate profile in two leaf types and in fruits. We estimated genetic variances and covariances (the G-matrix) and selection on chemical profile in each tissue. Chemical composition of defenses was strongly genetically correlated between tissues. We found antagonistic selection between defense composition in leaves and fruits: compounds that were favored in leaves were disadvantageous in fruits. The positive genetic correlations and antagonistic selection led to strong constraints on the evolution of defenses in leaves and fruits. In a hypothetical population with no genetic variation at BCMA1/3, we found no evidence for genetic constraints, indicating that pleiotropy affecting chemical profile in multiple tissues drives constraints on the evolution of secondary metabolites.
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