Evidence map›Paper›PMID 30949880›Full record

SynthesisMycopathologia2019

Fungal Keratitis Caused by Colletotrichum dematium: Case Study and Review.

Vladimír Buchta, Jana Nekolová, Naďa Jirásková, Radka Bolehovská, Jan Wipler, Vit Hubka

Abstract readCase ReportsSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Mycopathologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Use of corneal cross-linking beyond keratoconus: a systemic literature review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Pooled it
  2. Article
  3. Article
  4. A Sensitive Real-Time PCR-Based Assay for the Identification ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Rare case ofSouthern African journal of infectious diseases · 2026
    Article
  6. Review
  7. Diversity and Pathogenicity ofMicroorganisms · 2025
    Article
  8. Article
  9. Article
  10. Novel Pathogen-Plant Host Interaction:Plants (Basel, Switzerland) · 2023
    Article
  11. Journal of fungi (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Updating species diversity ofStudies in mycology · 2022
    Article
  14. Article
  15. First report of human infection caused byMedical mycology case reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vladimír BuchtaDepartment of Clinical Microbiology, University Hospital and Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Jana NekolováEye Clinic, University Hospital and Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Naďa JiráskováEye Clinic, University Hospital and Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Radka BolehovskáDepartment of Clinical Microbiology, University Hospital and Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Jan WiplerDepartment of Clinical Microbiology, University Hospital and Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Vit HubkaDepartment of Botany, Faculty of Science, Charles University, Prague, Czech Republic. hubka@biomed.cas.cz.ORCID http://orcid.org/0000-0003-4583-6496
Charles University · CZCzech Academy of Sciences · CZ

Funding

BIOCEV CZ.1.05/1.1.00/02.0109Charles University, Prague, Czech Republic PROGRES Q40/07Charles University Research Centre 204069
6 · The paper itself

Abstract

Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented. Infection was diagnosed based on positive microscopy and culture. The fungal isolate was identified by morphological characteristics and DNA sequencing of the ITS rDNA region, β-tubulin (tub2) and glyceraldehyde-3-phosphate dehydrogenase (gapdh) genes. The patient responded well to topical therapy with amphotericin B combined with intravenous amphotericin B but improvement was associated with the corneal collagen cross-linking. The review of the literature revealed another 13 cases of C. dematium keratitis, all but one patient having at least one keratitis risk factor in their history. Almost all patients (n = 12) were treated with topical polyene antibiotics (natamycin or amphotericin B), improvement and cure were achieved in eight of them.

Indexed as

Administration, TopicalAdolescentAdultAmphotericin BAntifungal AgentsColletotrichumDNA, Ribosomal SpacerEye InjuriesFemaleGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)HumansKeratitisMaleMicrobiological TechniquesMiddle AgedMolecular Diagnostic TechniquesAmphotericin BAntifungal AgentsDNA, Ribosomal SpacerGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)TubulinCoelomycetous fungiColletotrichum dematiumCorneal collagen cross-linkingGlomerellaKeratomycosisMolecular identificationTherapy

Identifiers

PMID30949880
OpenAlexW2929676399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.