Evidence map›Paper›PMID 30949873›Full record

ArticleClinical pharmacokinetics2019

Levothyrox

Didier Concordet, Peggy Gandia, Jean-Louis Montastruc, Alain Bousquet-Mélou, Peter Lees, Aude Ferran, Pierre-Louis Toutain

Abstract read
In one paragraph

Article in Clinical pharmacokinetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  7. Article
  8. Comment on "LevothyroxClinical pharmacokinetics · 2020
    Article
  9. Article
  10. Comment on "LevothyroxClinical pharmacokinetics · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Authors' Reply to Lechat et al.: "LevothyroxClinical pharmacokinetics · 2019
    Article
  15. Comment on: "LevothyroxClinical pharmacokinetics · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Didier ConcordetINTHERES, Université de Toulouse, INRA, ENVT, Toulouse, France.ORCID http://orcid.org/0000-0003-3916-577X
Peggy GandiaINTHERES, Université de Toulouse, INRA, ENVT, Toulouse, France.ORCID http://orcid.org/0000-0002-4385-7894
Jean-Louis MontastrucService de Pharmacologie Médicale et Clinique, INSERM UMR 1027, CIC INSERM 1436, Faculté de Médecine, Centre Hospitalier Universitaire de Toulouse, Université de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0001-6341-6001
Alain Bousquet-MélouINTHERES, Université de Toulouse, INRA, ENVT, Toulouse, France.ORCID http://orcid.org/0000-0002-7661-4311
Peter LeesRoyal Veterinary College, University of London, London, UK.
Aude FerranINTHERES, Université de Toulouse, INRA, ENVT, Toulouse, France.ORCID http://orcid.org/0000-0002-6629-1088
Pierre-Louis ToutainINTHERES, Université de Toulouse, INRA, ENVT, Toulouse, France. pltoutain@wanadoo.fr.ORCID http://orcid.org/0000-0002-8846-8892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In France, more than 2.5 million patients are currently treated with levothyroxine, mainly as the marketed product Levothyrox

Indexed as

Drug SubstitutionThyroxineClinical Trials as TopicDrug CompoundingEuropean UnionExcipientsHumansIntestinal AbsorptionLegislation, DrugMannitolTherapeutic EquivalencyUnited StatesUnited States Food and Drug AdministrationExcipientsMannitolThyroxine

Identifiers

PMID30949873
PMCPMC6584220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.