Evidence map›Paper›PMID 30949853›Full record

ArticleParasitology research2019

The dense granule protein 8 (GRA8) is a component of the sub-pellicular cytoskeleton in Toxoplasma gondii.

Rubén Darío Díaz-Martín, Corinne Mercier, Carmen T Gómez de León, Ricardo Mondragón González, Sirenia González Pozos, Emmanuel Ríos-Castro, Raúl Arguello García, Barbara A Fox, David J Bzik, Ricardo Mondragón Flores

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Rubén Darío Díaz-MartínDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Avenida IPN N°2508. Sn Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, CP, Mexico.
Corinne MercierLaboratoire Techniques de l'Imagerie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble (TIMC-IMAG), CNRS UMR 5525, Université Grenoble Alpes, Grenoble, France.
Carmen T Gómez de LeónDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Avenida IPN N°2508. Sn Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, CP, Mexico.
Ricardo Mondragón GonzálezDepartamento de Genética y Biología Molecular, CINVESTAV-IPN, Mexico City, Mexico.
Sirenia González PozosUnidad de Microscopía Electrónica (LaNSE), CINVESTAV-IPN, Mexico City, Mexico.
Emmanuel Ríos-CastroUnidad de Proteómica, Genómica y Metabolómica (LaNSE), CINVESTAV-IPN, Mexico City, Mexico.
Raúl Arguello GarcíaDepartamento de Genética y Biología Molecular, CINVESTAV-IPN, Mexico City, Mexico.
Barbara A FoxDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth , Lebanon, New Hampshire, USA.
David J BzikDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth , Lebanon, New Hampshire, USA.
Ricardo Mondragón FloresDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Avenida IPN N°2508. Sn Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, CP, Mexico. rmflores@cinvestav.mx.ORCID http://orcid.org/0000-0003-1913-9945
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXDartmouth College · USCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After host cell invasion, Toxoplasma secretes a variety of dense granule proteins (GRA proteins) from its secretory dense granules, which are involved in the biogenesis of the parasitophorous vacuole (PV). TgGRA8

Indexed as

ActinsAnimalsAntigens, ProtozoanBiological TransportCell MovementCytoskeletonMicroscopy, ImmunoelectronMicrotubulesMolecular Docking SimulationProteomicsProtozoan ProteinsSecretory VesiclesToxoplasmaToxoplasmosisTubulinVacuolesActinsAntigens, ProtozoanGRA4 protein, Toxoplasma gondiiGRA8 protein, Toxoplasma gondiiProtozoan ProteinsTubulinDense granulesMicrotubulesProline-rich proteinsToxoplasma cytoskeleton

Identifiers

PMID30949853
OpenAlexW2927786271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.