ArticleEuropean journal of clinical pharmacology2019
Use of prescription drugs in the older adult population-a nationwide pharmacoepidemiological study.
Article in European journal of clinical pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Cardiovascular and glucose-lowering medication use among older adults: results from 9-year follow-up of the FINGER trial.European geriatric medicine · 2026Trial
- An exploratory study on the impact of medication usage patterns on relapse among community schizophrenia patients.BMC psychiatry · 2026Article
- Commonly prescribed medicines antagonise anti-MRSA antibiotics and select for resistance.Microbiology (Reading, England) · 2026Article
- Healthcare workload associated with transition onto kidney replacement therapy: a retrospective cohort study.BMC nephrology · 2025Article
- Safety and Effectiveness of Apixaban in Very Elderly Patients with Atrial Fibrillation: A Retrospective Analysis of Japanese Administrative Claims Data.Cardiology and therapy · 2025Article
- The prevalence of polypharmacy increases with age among patients with inflammatory bowel disease: A nationwide cohort study.British journal of clinical pharmacology · 2025Article
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- Feasibility and Acceptability of Implementing a Digital Cognitive Assessment for Alzheimer Disease and Related Dementias in Primary Care.Annals of family medicine · 2025Article
- Polypharmacy Prevalence Among Older Adults Based on the Survey of Health, Ageing and Retirement in Europe: An Update.Journal of clinical medicine · 2025Article
- Number of medically prescribed pharmaceutical agents as predictor of mortality risk: a longitudinal, time-variable analysis in the EPIC-Heidelberg cohort.Scientific reports · 2024Article
- Drug prescriptions in elderly hospitalized patients with cognitive impairment in the Italian Dementia Friendly Hospital project.Frontiers in pharmacology · 2024Article
- Impact of lifestyle factors on dietary vitamin BThe British journal of nutrition · 2023Article
- Disentangling concepts of inappropriate polypharmacy in old age: a scoping review.BMC public health · 2023Article
- Polypharmacy and associated factors: a gender perspective in the elderly Spanish population (2011-2020).Frontiers in pharmacology · 2023Article
- Effectiveness of polypharmacy reduction policy in Japan: nationwide retrospective observational study.International journal of clinical pharmacy · 2022Observational
- Associations of the Severity of Obstructive Sleep Apnea With Age-Related Comorbidities: A Population-Based Study.Frontiers in neurology · 2022Article
- Article
- Analysis of the potential inappropriate use of medications in pediatric outpatients in China.BMC health services research · 2021Article
- Utility of suPAR and NGAL for AKI Risk Stratification and Early Optimization of Renal Risk Medications among Older Patients in the Emergency Department.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Use of Clopidogrel and Proton Pump Inhibitors Alone or in Combinations in Persons with Diabetes in Denmark; Potential for CYP2C19 Genotype-Guided Drug Therapy.Metabolites · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMulti-morbidity and polypharmacy are common among older people. It is essential to provide a better understanding of the complexity of prescription drug use among older adults to optimise rational pharmacotherapy. Population-based utilisation data in this age group is limited. Using the Danish nationwide health registries, we aimed to characterise drug use among Danish individuals ≥ 60 years.
methodsThis is a descriptive population-based study assessing drug prescription patterns in 2015 in the full Danish population aged ≥ 60 years. The use of specific therapeutic subgroups and chemical subgroups and its dependence on age were described using descriptive statistics. Profiles of drug combination patterns were evaluated using latent class analysis.
resultsWe included 1,424,775 residents (median age 70 years, 53% women). Of all the older adults, 89% filled at least one prescription during 2015. The median number of drug groups used was five per person. The most used single drug groups were paracetamol and analogues (34%), statins (33%) and platelet aggregation inhibitors (24%). Eighteen drug profiles with different drug combination patterns were identified. One drug profile with expected use of zero drugs and 11 drug profiles expected to receive more than five different therapeutic subgroup drugs were identified.
conclusionThe use of drugs is extensive both at the population level and increasing with age at an individual level. Separating the population into different homogenous groups related to drug use resulted in 18 different drug profiles, of which 11 drug profiles received on average more than five different therapeutic subgroup drugs.
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