Evidence map›Paper›PMID 30949508›Full record

Trial reportBioMed research international2019

Interleukin-1 Beta Gene Polymorphism rs16944 May Associate with Increased Susceptibility to Extremity Chronic Osteomyelitis in Chinese Han Population.

Zi-Long Yao, Qing-Rong Lin, Yan-Jun Hu, Yi-Long Hou, Yun-Fei Ma, Bin Yu, Nan Jiang

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zi-Long YaoDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Qing-Rong LinDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Yan-Jun HuDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Yi-Long HouDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Yun-Fei MaDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Bin YuDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0002-3109-2062
Nan JiangDepartment of Orthopaedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0003-2416-1653
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies had indicated that interleukin-1 beta (IL-1

methodsAltogether 233 extremity COM patients and 200 healthy controls were genotyped for the four tag SNPs of the IL-1

resultsSignificant associations were identified between rs16944 polymorphism and the risk of developing COM by dominant model (

conclusionsTo our knowledge, we reported for the first time that IL-1

Indexed as

Asian PeopleGene FrequencyGenetic Predisposition to DiseaseOsteomyelitisPolymorphism, Single NucleotideAdultChinaChronic DiseaseFemaleHumansInterleukin-1betaMaleMiddle AgedIL1B protein, humanInterleukin-1beta

Identifiers

PMID30949508
PMCPMC6425336
OpenAlexW2920059887

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.