Evidence map›Paper›PMID 30949171›Full record

Observational studyFrontiers in immunology2019

Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus.

László József Barkai, Emese Sipter, Dorottya Csuka, Zoltán Prohászka, Katrine Pilely, Peter Garred, Nóra Hosszúfalusi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Antibiotic exposure and risk of type 2 diabetes mellitus: a systematic review and meta-analysis.Environmental science and pollution research international · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Deimination Protein Profiles inFrontiers in immunology · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

László József Barkai3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Emese Sipter3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Dorottya Csuka3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Zoltán Prohászka3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Katrine PilelyLaboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Peter GarredLaboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nóra Hosszúfalusi3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Semmelweis University · HURigshospitalet · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections are frequent and severe in patients with diabetes mellitus. Whether diabetes

Indexed as

AgedAged, 80 and overComplement Pathway, AlternativeComplement Pathway, Mannose-Binding LectinDiabetes Mellitus, Type 2Escherichia coliEscherichia coli InfectionsFemaleHumansLectinsMaleMiddle AgedProspective StudiesUrinary Tract InfectionsFCN3 protein, humanLectinsalternative pathwaybacterial infectionclassical pathwaycomplementEscherichia colificolin-3lectin pathwaytype 2 diabetes

Identifiers

PMID30949171
PMCPMC6436462
OpenAlexW2924684394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.