ArticleFrontiers in immunology2019
Extensive Ethnic Variation and Linkage Disequilibrium at the
Open access · goldAbstract read
In one paragraph
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Association between IL10 rs1800896 polymorphism and risk of pediatric asthma: A meta-analysis.The clinical respiratory journal · 2023Pooled it
- MicroRNAs in Kawasaki disease: An update on diagnosis, therapy and monitoring.Frontiers in immunology · 2022Pooled it
- The Autophagy-Inflammasome Axis as a Molecular Switch: From Persistent Inflammation to Vascular Remodeling in IVIG-Resistant Kawasaki Disease.International journal of molecular sciences · 2026Review
- Large deletions in theResearch and practice in thrombosis and haemostasis · 2025Article
- Genetic variation of low-to-medium-affinity Fc-gamma receptors in Guillain-Barré syndrome.Journal of neurology · 2025Article
- Therapeutic potential of tumor-associated neutrophils: dual role and phenotypic plasticity.Signal transduction and targeted therapy · 2025Review
- Polymorphism-driven immune disruptions in Kawasaki disease across populations: decoding the role of T and B-cells.Frontiers in immunology · 2025Review
- Endothelial Dysfunction: Molecular Mechanisms and Therapeutic Strategies in Kawasaki Disease.International journal of molecular sciences · 2024Review
- Neutrophil diversity and function in health and disease.Signal transduction and targeted therapy · 2024Review
- Pitfalls When Determining HNA-1 Genotypes and Finding Novel Alleles.International journal of molecular sciences · 2024Article
- Fcγ receptors and immunomodulatory antibodies in cancer.Nature reviews. Cancer · 2024Review
- Article
- Analysis of FCGR3A-p.176Val variants in women with recurrent pregnancy loss and the association with CD16a expression and anti-HLA antibody status.Scientific reports · 2023Article
- Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity.EBioMedicine · 2022Article
- Fc receptors and the diversity of antibody responses to HIV infection and vaccination.Genes and immunity · 2022Review
- Gut Microbiota Dysbiosis in Childhood Vasculitis: A Perspective Comparative Pilot Study.Journal of personalized medicine · 2022Article
- Article
- FCGR3A gene duplication, FcγRIIb-232TT and FcγRIIIb-HNA1a associate with an increased risk of vertical acquisition of HIV-1.PloS one · 2022Article
- FCGR2C: An emerging immune gene for predicting sepsis outcome.Frontiers in immunology · 2022Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 13 institutions in 7 countries.
Sietse Q NagelkerkeDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Carline E TackePediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Willemijn B BreunisPediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Michael W T TanckDepartment of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Judy GeisslerDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Eileen PngInfectious Diseases, Genome Institute of Singapore, Singapore, Singapore.
Long T HoangInfectious Diseases, Genome Institute of Singapore, Singapore, Singapore.
Joris van der HeijdenDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Ahmad N M NaimInfectious Diseases, Genome Institute of Singapore, Singapore, Singapore.
Rae S M YeungDivision of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Michael L LevinDepartment of Pediatrics, Imperial College London, London, United Kingdom.
Victoria J WrightDepartment of Pediatrics, Imperial College London, London, United Kingdom.
David P BurgnerMurdoch Children's Research Institute, Royal Children's Hospital, Melbourne, VIC, Australia.
Anne-Louise PonsonbyMurdoch Children's Research Institute, Royal Children's Hospital, Melbourne, VIC, Australia.
Justine A EllisMurdoch Children's Research Institute, Royal Children's Hospital, Melbourne, VIC, Australia.
Rolando CimazRheumatology Unit, Meyer Children's Hospital, University of Florence, Florence, Italy.
Chisato ShimizuDepartment of Pediatrics, University of California San Diego School of Medicine, La Jolla, CA, United States.
Jane C BurnsDepartment of Pediatrics, University of California San Diego School of Medicine, La Jolla, CA, United States.
Karin FijnvandraatPediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
C Ellen van der SchootDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Timo K van den BergDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Martin de BoerDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Sonia DavilaHuman Genetics, Genome Institute of Singapore, Singapore, Singapore.
Martin L HibberdInfectious Diseases, Genome Institute of Singapore, Singapore, Singapore.
Taco W KuijpersDepartment of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
International Kawasaki Disease Genetics Consortium
University of Amsterdam · NLGenome Institute of Singapore · SGAmsterdam University Medical Centers · NLImperial College London · GBSanquin · NLUniversity of California, San Diego · USDeakin University · AUEmma Kinderziekenhuis · NLHospital for Sick Children · CALondon School of Hygiene & Tropical Medicine · GBMurdoch Children's Research Institute · AURoyal Children's Hospital · AUUniversity of Florence · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human Fc-gamma receptors (FcγRs) link adaptive and innate immunity by binding immunoglobulin G (IgG). All human low-affinity FcγRs are encoded by the
Indexed as
Genetic Association StudiesGenetic LociGenetic Predisposition to DiseaseLinkage DisequilibriumAllelesCase-Control StudiesDNA Copy Number VariationsEthnicityGene Expression ProfilingGene FrequencyGenome-Wide Association StudyGenotypeHaplotypesHumansMucocutaneous Lymph Node SyndromeOdds RatioReceptors, IgGFc-gamma receptorFCGR polymorphismimmunogeneticsKawasaki disease (KD)linkage disequilibrium
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.