Evidence map›Paper›PMID 30949136›Full record

ArticleFrontiers in microbiology2019

Dysbiosis of Skin Microbiota in Psoriatic Patients: Co-occurrence of Fungal and Bacterial Communities.

Zuzana Stehlikova, Martin Kostovcik, Klara Kostovcikova, Miloslav Kverka, Katerina Juzlova, Filip Rob, Jana Hercogova, Petr Bohac, Yishay Pinto, Atara Uzan and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Article
  9. Article
  10. Article
  11. Towards sustainable antimicrobial therapies forSustainable microbiology · 2024
    Review
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  15. Article
  16. The Role of Yeasts in Human Health: A Review.Life (Basel, Switzerland) · 2023
    Review
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  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Zuzana StehlikovaInstitute of Microbiology, Czech Academy of Sciences, Prague, Czechia.
Martin KostovcikInstitute of Microbiology, Czech Academy of Sciences, Prague, Czechia.
Klara KostovcikovaInstitute of Microbiology, Czech Academy of Sciences, Prague, Czechia.
Miloslav KverkaInstitute of Microbiology, Czech Academy of Sciences, Prague, Czechia.
Katerina JuzlovaBulovka Hospital, Dermatovenerology Department, Second Faculty of Medicine, Charles University in Prague, Prague, Czechia.
Filip RobBulovka Hospital, Dermatovenerology Department, Second Faculty of Medicine, Charles University in Prague, Prague, Czechia.
Jana HercogovaBulovka Hospital, Dermatovenerology Department, Second Faculty of Medicine, Charles University in Prague, Prague, Czechia.
Petr BohacBulovka Hospital, Dermatovenerology Department, Second Faculty of Medicine, Charles University in Prague, Prague, Czechia.
Yishay PintoThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Atara UzanThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Omry KorenThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Helena Tlaskalova-HogenovaInstitute of Microbiology, Czech Academy of Sciences, Prague, Czechia.
Zuzana Jiraskova ZakostelskaInstitute of Microbiology, Czech Academy of Sciences, Prague, Czechia.
Czech Academy of Sciences, Institute of Microbiology · CZCharles University · CZBar-Ilan University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin disease, whose pathogenesis involves dysregulated interplay among immune cells, keratinocytes and environmental triggers, including microbiota. Bacterial and fungal dysbiosis has been recently associated with several chronic immune-mediated diseases including psoriasis. In this comprehensive study, we investigated how different sampling sites and methods reflect the uncovered skin microbiota composition. After establishing the most suitable approach, we further examined correlations between bacteria and fungi on the psoriatic skin. We compared microbiota composition determined in the same sample by sequencing two distinct hypervariable regions of the 16S rRNA gene. We showed that using the V3V4 region led to higher species richness and evenness than using the V1V2 region. In particular, genera, such as

Indexed as

microbiotamycobiotapsoriasissequencingskin

Identifiers

PMID30949136
PMCPMC6437110
OpenAlexW2924876411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.