ArticleFrontiers in psychiatry2019
Abnormal Degree Centrality Associated With Cognitive Dysfunctions in Early Bipolar Disorder.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Altered voxel-wise degree centrality of brain networks in patients with chronic rhinosinusitis: a resting-state functional magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2025Article
- Altered Brain-Behavior Association During Resting State is a Potential Psychosis Risk Marker.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Degree centrality values in the left calcarine as a potential imaging biomarker for anxious major depressive disorder.World journal of psychiatry · 2025Article
- Cognitive Decline in Patients With Trigeminal Neuralgia: A Resting-State fMRI Study.Brain and behavior · 2025Article
- Aberrant resting-state functional network centrality and cognitive impairment in unmedicated, euthymic bipolar patients.BMC psychiatry · 2024Article
- Decreased dynamic variability of the cerebellum in the euthymic patients with bipolar disorder.BMC psychiatry · 2024Article
- Identifying misdiagnosed bipolar disorder using support vector machine: feature selection based on fMRI of follow-up confirmed affective disorders.Translational psychiatry · 2024Article
- Altered brain network centrality in patients with orbital fracture: A resting‑state functional MRI study.Experimental and therapeutic medicine · 2023Article
- Abnormal hubs in global network as potential neuroimaging marker in generalized anxiety disorder at rest.Frontiers in psychology · 2022Article
- Structure can predict function in the human brain: a graph neural network deep learning model of functional connectivity and centrality based on structural connectivity.Brain structure & function · 2022Article
- Abnormal Voxel-Based Degree Centrality in Patients With Postpartum Depression: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2022Article
- Shared and distinct patterns of dynamical degree centrality in bipolar disorder across different mood states.Frontiers in psychiatry · 2022Article
- Abnormal degree centrality in first-episode medication-free adolescent depression at rest: A functional magnetic resonance imaging study and support vector machine analysis.Frontiers in psychiatry · 2022Article
- Comparison of resting-state spontaneous brain activity between treatment-naive schizophrenia and obsessive-compulsive disorder.BMC psychiatry · 2021Article
- Comparison of Cerebellar Grey Matter Alterations in Bipolar and Cerebellar Patients: Evidence from Voxel-Based Analysis.International journal of molecular sciences · 2021Article
- Altered Gray Matter Volume, Functional Connectivity, and Degree Centrality in Early-Onset Type 2 Diabetes Mellitus.Frontiers in neurology · 2021Article
- The characteristic of cognitive impairments in patients with bipolar II depression and its association with N-acetyl aspartate of the prefrontal white matter.Annals of translational medicine · 2020Article
- Alterations in Degree Centrality and Functional Connectivity in Parkinson's Disease Patients With Freezing of Gait: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2020Article
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13 authors.
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Abstract
Delayed diagnosis of bipolar disorder (BD) is common. However, diagnostic validity may be enhanced using reliable neurobiological markers for BD. Degree centrality (DC) is one such potential marker that enables researchers to visualize neuronal network abnormalities in the early stages of some neuropsychiatric disorders. In the present study, we measured resting-state DC abnormalities and cognitive deficits in order to identify early neurobiological markers for BD. We recruited 23 patients with BD who had recently experienced manic episodes (duration of illness <2 years) and 46 matched healthy controls. Our findings indicated that patients with BD exhibited DC abnormalities in frontal areas, temporal areas, the right postcentral gyrus, and the posterior lobe of the cerebellum. Moreover, correlation analysis revealed that psychomotor speed indicators were associated with DC in the superior temporal and inferior temporal gyri, while attention indicators were associated with DC in the inferior temporal gyrus, in patients with early BD. Our findings suggest that DC abnormalities in neural emotion regulation circuits are present in patients with early BD, and that correlations between attention/psychomotor speed deficits and temporal DC abnormalities may represent early markers of BD.
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