Evidence map›Paper›PMID 30948609›Full record

ArticleBMJ open2019

Opioid use disorder in chronic non-cancer pain in Germany: a cross sectional study.

Johannes Maximilian Just, Fabian Schwerbrock, Markus Bleckwenn, Rieke Schnakenberg, Klaus Weckbecker

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  7. [How long does a long-term therapy last?]Schmerz (Berlin, Germany) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Johannes Maximilian JustInstitute of General Practice and Family Medicine, Universitatsklinikum Bonn, Bonn, Germany.
Fabian SchwerbrockInstitute of General Practice and Family Medicine, Universitatsklinikum Bonn, Bonn, Germany.
Markus BleckwennInstitute of General Practice and Family Medicine, Universitatsklinikum Bonn, Bonn, Germany.
Rieke SchnakenbergDepartment für Versorgungsforschung, Carl von Ossietzky University Oldenburg, Oldenburg, UK.
Klaus WeckbeckerInstitute of General Practice and Family Medicine, Universitatsklinikum Bonn, Bonn, Germany.
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe DSM-5 diagnosis 'opioid use disorder' (OUD) was established to better describe and detect significant impairment or distress related to opioid use. There is no data on rates of OUD in chronic non-cancer pain (CNCP) in European countries. Therefore, our objective was to screen patients in specialised pain centres for signs of OUD.

designCross-sectional questionnaire study.

settingFour outpatient pain clinics in the area of Bonn, Germany.

participantsn=204 patients participated in the study (response rate: 87.9%). All adult patients with opioid pain therapy >6 months for CNCP were included. Excluded were patients with malignant disease, patients who could not collect their prescription themselves due to age or multimorbidity and patients on opioid-maintenance therapy. PRIMARY AND SECONDARY OUTCOME MEASURE: Primary outcome measure was the proportion of patients with mild to severe OUD.

resultsOne-fourth (26.5%) of participants were diagnosed with OUD. Moderate to severe disorder was found in 9.3. Young age was the only connected risk factor (OR 0.96 [95% CI 0.94 to 0.99], p: 0.003).

conclusionsOUD is a relevant diagnosis in patients on long-term opioid therapy for CNCP in the Bonn area. Careful follow-up by the attending physicians is advisable, especially in patients with moderate or severe disorder.

Indexed as

AdultAgedAged, 80 and overAnalgesics, OpioidChronic PainCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedOpioid-Related DisordersRisk FactorsSeverity of Illness IndexSurveys and QuestionnairesAnalgesics, Opioidopioid use disorderprescription opioidsprevalence

Identifiers

PMID30948609
PMCPMC6500335
OpenAlexW2932016946

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.