Evidence map›Paper›PMID 30948521›Full record

SynthesisOccupational and environmental medicine2019

Welding fumes and lung cancer: a meta-analysis of case-control and cohort studies.

Manoj Kumar Honaryar, Ruth M Lunn, Danièle Luce, Wolfgang Ahrens, Andrea 't Mannetje, Johnni Hansen, Liacine Bouaoun, Dana Loomis, Graham Byrnes, Nadia Vilahur and 2 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Welding Fumes, a Risk Factor for Lung Diseases.International journal of environmental research and public health · 2020
    Pooled it
  5. Welding and brazing fumes and lung cancer risk: a systematic review and meta-analysis.Journal of occupational medicine and toxicology (London, England) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Physical working conditions over time: a repeated cross-sectional study in German employees.Journal of occupational medicine and toxicology (London, England) · 2024
    Article
  13. Review
  14. Review
  15. Occupational Etiology of Oropharyngeal Cancer: A Literature Review.International journal of environmental research and public health · 2023
    Review
  16. Review
  17. Article
  18. Effects of Tobacco Smoking on the Survivability of Patients with Multiple Cancers and Single Lung Cancer.International journal of environmental research and public health · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 6 countries.

Manoj Kumar HonaryarInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-6784-0309
Ruth M LunnNational Institute of Environmental Health Sciences, Durham, North Carolina, USA.ORCID 0000-0002-9605-7137
Danièle LuceUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, France.
Wolfgang AhrensLeibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.ORCID 0000-0003-3777-570X
Andrea 't MannetjeCentre for Public Health Research, Massey University, Wellington, New Zealand.
Johnni HansenDanish Cancer Society Research Center, København, Denmark.ORCID 0000-0002-9342-2725
Liacine BouaounInternational Agency for Research on Cancer, Lyon, France.
Dana LoomisInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-3297-5200
Graham ByrnesInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-3893-7539
Nadia VilahurInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-6641-5143
Leslie StaynerDivision of Epidemiology and Biostatistics, University of Illinois, School of Public Health, Chicago, Illinois, USA.
Neela GuhaInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-3991-4662
Centre international de recherche sur le cancer · FRDanish Cancer Society · DKÉcole des Hautes Études en Santé Publique · FREuropean Commission · BEInserm · FRLeibniz Institute for Prevention Research and Epidemiology - BIPS · DEMassey University · NZNational Institute of Environmental Health Sciences · USUniversity of Illinois Urbana-Champaign · USUniversity of Nevada, Reno · US

Funding

Integrated Health Assessments for the Division of the National Toxicology ProgramZICES103317 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ROONEY, ANDREW · 2020 to 2021
$9.6M
Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIC ES103317World Health Organization 001
6 · The paper itself

Abstract

backgroundAn estimated 110 million workers are exposed to welding fumes worldwide. Welding fumes are classified by the International Agency for Research on Cancer as

objectiveTo conduct a meta-analysis of case-control and cohort studies on welding or exposure to welding fumes and risk of lung cancer, accounting for confounding by exposure to asbestos and tobacco smoking.

methodsThe literature was searched comprehensively in PubMed, reference lists of relevant publications and additional databases. Overlapping populations were removed. Meta-relative risks (mRRs) were calculated using random effects models. Publication bias was assessed using funnel plot, Eggers's test and Begg's test.

resultsForty-five studies met the inclusion criteria (20 case-control, 25 cohort/nested case-control), which reduced to 37 when overlapping study populations were removed. For 'ever' compared with 'never' being a welder or exposed to welding fumes, mRRs and 95% CIs were 1.29 (1.20 to 1.39; I

conclusionsThese results support the conclusion that exposure to welding fumes increases the risk of lung cancer, regardless of the type of steel welded, the welding method (arc vs gas welding) and independent of exposure to asbestos or tobacco smoking.

Indexed as

Air Pollutants, OccupationalCase-Control StudiesCohort StudiesHumansLung NeoplasmsOccupational ExposureWeldingAir Pollutants, Occupationalarc weldingexposure-effect analysisgas weldinglung cancermeta-analysismeta-regressionmild steel weldingstainless steel weldingweldingwelding fumes

Identifiers

PMID30948521
PMCPMC13527568
OpenAlexW2929494731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.