Evidence map›Paper›PMID 30948018›Full record

ReviewMethods in cell biology2019

Generation, expression and utilization of single-domain antibodies for in vivo protein localization and manipulation in sea urchin embryos.

Catherine S Schrankel, Tufan Gökirmak, Chang-Wook Lee, Geoffrey Chang, Amro Hamdoun

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Methods in cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Good reasons for targeting SARS-CoV-2 by engineered extracellular vesicles.Molecular therapy. Methods & clinical development · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Catherine S SchrankelMarine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, San Diego, CA, United States.
Tufan GökirmakMarine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, San Diego, CA, United States.
Chang-Wook LeeDepartment of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, United States.
Geoffrey ChangDepartment of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, United States.
Amro HamdounMarine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, San Diego, CA, United States. Electronic address: ahamdoun@ucsd.edu.
University of California, San Diego · USScripps Institution of Oceanography · US

Funding

Identity, mechanisms and early life impacts of transporter interfering compoundsR01ES027921 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, GEOFFREY A, HAMDOUN, AMRO M · 2018 to 2022
$3.0M
Molecular Mechanisms of Marine Organohalogen Bioaccumulation and NeurotoxicityR01ES030318 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMDOUN, AMRO M, PESSAH, ISAAC N · 2018 to 2022
$826k
Identifying the ABCs of xenobiotic metabolism in protecting the germ line lineageF32ES029843 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHRANKEL, CATHERINE SARAH · 2018 to 2022
$238k
NIEHS NIH HHS F32 ES029843NIEHS NIH HHS R01 ES027921NIEHS NIH HHS R01 ES030318
6 · The paper itself

Abstract

Single-domain antibodies, also known as nanobodies, are small antigen-binding fragments (~15kDa) that are derived from heavy chain only antibodies present in camelids (V

Indexed as

AnimalsCamelids, New WorldCamelusEmbryonic DevelopmentEmbryo, NonmammalianImmunoglobulin Heavy ChainsMolecular BiologyProteinsProtein TransportSea UrchinsSingle-Domain AntibodiesImmunoglobulin Heavy ChainsProteinsSingle-Domain AntibodiesChromobodyDevelopmentLive-cell antigen taggingmRNA overexpressionNanobody

Identifiers

PMID30948018
PMCPMC6489465
OpenAlexW2922053747

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.