Evidence map›Paper›PMID 30947682›Full record

ArticleBMC genomics2019

Genome-wide association studies targeting the yield of extraembryonic fluid and production traits in Russian White chickens.

Andrei A Kudinov, Natalia V Dementieva, Olga V Mitrofanova, Olga I Stanishevskaya, Elena S Fedorova, Tatiana A Larkina, Arina I Mishina, Kirill V Plemyashov, Darren K Griffin, Michael N Romanov

Abstract read
In one paragraph

Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrei A KudinovRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Natalia V DementievaRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Olga V MitrofanovaRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Olga I StanishevskayaRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Elena S FedorovaRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Tatiana A LarkinaRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Arina I MishinaRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Kirill V PlemyashovRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.
Darren K GriffinSchool of Biosciences, University of Kent, Canterbury, Kent, CT2 7NJ, UK. D.K.Griffin@kent.ac.uk.ORCID http://orcid.org/0000-0001-7595-3226
Michael N RomanovRussian Research Institute of Farm Animal Genetics and Breeding Branch of the L. K. Ernst Federal Science Centre for Animal Husbandry, Pushkin, St Petersburg, 196601, Russia.

Funding

Russian Science Foundation 16-16-04060
6 · The paper itself

Abstract

backgroundThe Russian White is a gene pool breed, registered in 1953 after crossing White Leghorns with local populations and, for 50 years, selected for cold tolerance and high egg production (EL). The breed has great potential in meeting demands of local food producers, commercial farmers and biotechnology sector of specific pathogen-free (SPF) eggs, the former valuing the breed for its egg weight (EW), EL, age at first egg (AFE), body weight (BW), and the latter for its yield of extraembryonic fluid (YEF) in 12.5-day embryos, ratio of extraembryonic fluid to egg weight, and embryo mass. Moreover, its cold tolerance has been presumably associated with day-old chick down colour (DOCDC) - white rather than yellow, the genetic basis of these traits being however poorly understood.

resultsWe undertook genome-wide association studies (GWASs) for eight performance traits using single nucleotide polymorphism (SNP) genotyping of 146 birds and an Illumina 60KBeadChip. Several suggestive associations (p < 5.16*10

conclusionsThe obtained GWAS data can be used to explore the genetics of immunity and carry out selection for increasing YEF for SPF eggs production.

Indexed as

EggsGenome-Wide Association StudyQuantitative Trait, HeritableAmniotic FluidAnimalsChickensFemaleLinkage DisequilibriumPhenotypeDay-old chick down colourGWASPoultryRussian white chicken breedSNPYield of extraembryonic fluid

Identifiers

PMID30947682
PMCPMC6449956

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.