Evidence map›Paper›PMID 30947302›Full record

ArticlePLoS pathogens2019

A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen.

Nicholas Raffa, Nancy P Keller

Registry-linked trialAbstract read
In one paragraph

Article in PLoS pathogens, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05860387 (Early Diagnosis of Invasive Lung Aspergillosis), which is not on this map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05860387 recruitingnot on this mapstarted 2023, after this paper: background citation

Early Diagnosis of Invasive Lung Aspergillosis

TypeobservationalSponsorUniversity Hospital OstravaRan2023 to 2026Enrolled150ConditionsRespiratory Infection, Invasive Pulmonary AspergillosisArmsNext generation improvement of early invasive aspergillosis
3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Article
  2. Repurposing FDA-Approved Drugs to Inhibit Fungal PPTases for Broad-Spectrum Synergy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Opportunistic pathogenicity in fungi can transcend species boundaries.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Confrontations betweenApplied and environmental microbiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Whole-chromosome duplications drive antimicrobial resistance inbioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Progress in Gliotoxin Research.Molecules (Basel, Switzerland) · 2025
    Review
  17. Article
  18. mBio · 2025
    Article
  19. Journal of microbiology and biotechnology · 2025
    Review
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicholas RaffaDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.ORCID 0000-0003-0112-5262
Nancy P KellerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.ORCID 0000-0002-4386-9473

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
Mechanisms of an Aspergillus fumigatus virulence mutantR01AI065728 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KELLER, NANCY P · 2006 to 2017
$3.6M
NIAID NIH HHS R01 AI065728NIGMS NIH HHS T32 GM008349
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MetabolomeAnti-Bacterial AgentsAspergillosisAspergillus fumigatusHost-Pathogen InteractionsHumansOpportunistic InfectionsAnti-Bacterial Agents

Identifiers

PMID30947302
PMCPMC6448812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.